SCHEMBL434767

SCHEMBL434767

O=C(O)CCc1ncc[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.74
TERT O14746 1/20 0.46
CHRM1 P11229 1/20 0.45
TAAR1 Q96RJ0 4/20 0.44
FDPS P14324 1/20 0.43
ALOX15 P16050 1/20 0.41
GAA P10253 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
APEX1 P27695 1/20 0.41
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PRKAB1 Q9Y478 1/20 0.39
PARP1 P09874 1/20 0.39
PARP2 Q9UGN5 1/20 0.39
FPR2 P25090 1/20 0.39
HTR1A P08908 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30620153 1.00 TBXAS1 (0.74) TBXAS1TERTCHRM1TAAR1FDPS
Hydrochloric Acid SCHEMBL28313785 0.98 TBXAS1 (0.72) TBXAS1TERTCHRM1TAAR1FDPS
Hydrochloric Acid SCHEMBL11095352 0.98 TBXAS1 (0.75) TBXAS1TERTCHRM1TAAR1FDPS
Hydrochloric Acid SCHEMBL8937731 0.98 TBXAS1 (0.75) TBXAS1TERTCHRM1TAAR1FDPS
Bromide SCHEMBL28875643 0.98 TBXAS1 (0.72) TBXAS1TERTCHRM1TAAR1FDPS
Sulfuric Acid SCHEMBL28313783 0.93 TBXAS1 (0.66) TBXAS1TERTCHRM1TAAR1FDPS
SCHEMBL8979265 0.89 TBXAS1 (0.87) TBXAS1TERTTAAR1FDPSALOX15
Hydrochloric Acid SCHEMBL11657876 0.87 TBXAS1 (0.87) TBXAS1TERTTAAR1FDPSALOX15
SCHEMBL4655987 0.87 TBXAS1 (0.97) TBXAS1TERTTAAR1FDPS
SCHEMBL7051672 0.85 TBXAS1 (1.00) TBXAS1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 451 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121528553-B Sepsis myocardial function prognosis prediction method based on imidazole propionic acid targeted intervention Zhoupu Hospital, Pudong New Area, Shanghai (Zhoupu Hospital Affiliated to Shanghai Medical College) (CN) 2026-05-26 CN claimed
US-20260000770-A1 LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF BEIJING QL BIOPHARMACEUTICAL CO LTD (CN) 2026-01-01 US claimed
WO-2025226506-A1 MONO- AND DUAL-AGONIST COMPOUNDS OF HUMAN GLP1R AND GIPR FOR OBESITY & T2DM PROTAGONIST THERAPEUTICS, INC. (US) 2025-10-30 WO claimed
US-20250276068-A1 PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF BEIJING QL BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-04 US claimed
US-20240424011-A1 COMBINATION THERAPY OF HYPOXIA-RESPONSIVE PRODRUG OF AN ANTICANCER DRUG AND RADIOTHERAPY, AND NOVEL HYPOXIA-RESPONSIVE PRODRUG UNIVERSITY OF TSUKUBA (JP) 2024-12-26 US claimed
EP-4454646-A1 COMBINATION THERAPY INVOLVING RADIOTHERAPY AND HYPOXIA-RESPONSIVE PRODRUG OF ANTICANCER DRUG, AND NOVEL HYPOXIA-RESPONSIVE PRODRUG University of Tsukuba (JP) 2024-10-30 EP claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-20240181016-A1 POLYPEPTIDE CONJUGATES AND METHODS OF USES BEIJING QL BIOPHARMACEUTICAL CO., LTD. (CN) 2024-06-06 US claimed
EP-4337244-A1 PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF Beijing QL Biopharmaceutical Co., Ltd. (CN) 2024-03-20 EP claimed
CN-117598247-A Application of imidazole propionic acid in preparation of modeling agent for inducing ulcerative colitis animal model 天津中医药大学 2024-02-27 CN claimed
WO-2009137291-A2 SPIROAZAINDOLES MERCK & CO., INC. (US) 2009-11-12 WO claimed
JP-3759748-B2 2006-03-29 JP claimed
CN-1085980-C Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists SEARLE & CO (US) 2002-06-05 CN claimed
EP-0736038-B1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK AS (DK) 2001-07-04 EP claimed
CN-1052730-C Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 2000-05-24 CN claimed
US-5854211-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1998-12-29 US claimed
CN-1138334-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1996-12-18 CN claimed
EP-0736038-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1996-10-09 EP claimed
EP-0604368-B1 Anti retroviral hydrazine derivatives CIBA GEIGY AG (CH) 1996-09-18 EP claimed
WO-1995017422-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1995-06-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240181016-A1 POLYPEPTIDE CONJUGATES AND METHODS OF USES GLP1R, GIPR, IAPP TBXAS1 2422/4885TERT 3965/4885CHRM1 2407/4885
US-20250276068-A1 PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF GLP1R, GIPR, IAPP TBXAS1 1782/4885TERT 4220/4885CHRM1 2062/4885
US-20240424011-A1 COMBINATION THERAPY OF HYPOXIA-RESPONSIVE PRODRUG OF AN ANTICANCER DRUG AND RADIOTHERAPY, AND NOVEL HYPOXIA-RESPONSIVE PRODRUG HIF1AN, HIF1A, PAICS TBXAS1 1408/4885TERT 419/4885CHRM1 4736/4885
US-20260000770-A1 LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF GLP1R, GIPR, VIP TBXAS1 1548/4885TERT 4464/4885CHRM1 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.