Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.72 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434767 | 0.98 | TBXAS1 (0.74) | TBXAS1TERTCHRM1TAAR1FDPS | |
| SCHEMBL30620153 | 0.98 | TBXAS1 (0.74) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL28313785 | 0.96 | TBXAS1 (0.72) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL11095352 | 0.96 | TBXAS1 (0.75) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL8937731 | 0.96 | TBXAS1 (0.75) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Sulfuric Acid SCHEMBL28313783 | 0.91 | TBXAS1 (0.66) | TBXAS1TERTCHRM1TAAR1FDPS | |
| SCHEMBL8979265 | 0.87 | TBXAS1 (0.87) | TBXAS1TERTTAAR1FDPSALOX15 | |
| Hydrochloric Acid SCHEMBL11657876 | 0.85 | TBXAS1 (0.87) | TBXAS1TERTTAAR1FDPSALOX15 | |
| SCHEMBL4655987 | 0.85 | TBXAS1 (0.97) | TBXAS1TERTTAAR1FDPS | |
| SCHEMBL7051672 | 0.84 | TBXAS1 (1.00) | TBXAS1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041533-A | A kind of method that ionic liquid ligand displacement method prepares functional metal organic framework material | 福州大学 | 2019-07-23 | — | — | CN | claimed |
| CN-110041533-A | A kind of method that ionic liquid ligand displacement method prepares functional metal organic framework material | 福州大学 | 2019-07-23 | — | — | CN | disclosed |