Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.66 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620153 | 0.93 | TBXAS1 (0.74) | TBXAS1TERTCHRM1TAAR1FDPS | |
| SCHEMBL434767 | 0.93 | TBXAS1 (0.74) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL28313785 | 0.91 | TBXAS1 (0.72) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL8937731 | 0.91 | TBXAS1 (0.75) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Hydrochloric Acid SCHEMBL11095352 | 0.91 | TBXAS1 (0.75) | TBXAS1TERTCHRM1TAAR1FDPS | |
| Bromide SCHEMBL28875643 | 0.91 | TBXAS1 (0.72) | TBXAS1TERTCHRM1TAAR1FDPS | |
| SCHEMBL8979265 | 0.82 | TBXAS1 (0.87) | TBXAS1TERTTAAR1FDPSGAA | |
| SCHEMBL4655987 | 0.81 | TBXAS1 (0.97) | TBXAS1TERTTAAR1FDPS | |
| Hydrochloric Acid SCHEMBL11657876 | 0.81 | TBXAS1 (0.87) | TBXAS1TERTTAAR1FDPSGAA | |
| SCHEMBL11009198 | 0.79 | TBXAS1 (1.00) | TBXAS1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041533-A | A kind of method that ionic liquid ligand displacement method prepares functional metal organic framework material | 福州大学 | 2019-07-23 | — | — | CN | claimed |
| CN-110041533-A | A kind of method that ionic liquid ligand displacement method prepares functional metal organic framework material | 福州大学 | 2019-07-23 | — | — | CN | disclosed |