Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958208 | 0.81 | ELANE (0.45) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL1949305 | 0.80 | GAA (0.42) | MAPTKMT2ASMN1; SMN2GAAESR1 | |
| SCHEMBL29117706 | 0.76 | ALDH1A1 (0.54) | MAPTKMT2ASMN1; SMN2GAAMEN1 | |
| SCHEMBL27395930 | 0.76 | ALDH1A1 (0.40) | MAPTKMT2ASMN1; SMN2MEN1HSD17B10 | |
| SCHEMBL28021298 | 0.76 | ALDH1A1 (0.45) | MAPTKMT2ASMN1; SMN2GAAMEN1 | |
| SCHEMBL27764007 | 0.75 | CES2 (0.39) | MAPTKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL3039305 | 0.73 | AKR1C1 (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL3039302 | 0.73 | AKR1C1 (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL348321 | 0.73 | AKR1C1 (0.53) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 | |
| SCHEMBL6971325 | 0.72 | CES1 (0.44) | MAPTKMT2ASMN1; SMN2MEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281234-A1 | MANUFACTURING METHOD OF THERMOPLASTIC COMPOSITE MATERIAL, THERMOPLASTIC COMPOSITE MATERIAL AND OPTICAL ELEMENT | KONICA MINOLTA OPTO, INC. (JP) | 2009-11-12 | — | — | US | disclosed |