Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.63 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890795 | 0.87 | FFAR1 (0.47) | FFAR1PPARGPPARACYP4F2CYP4A11 | |
| SCHEMBL4266308 | 0.82 | FFAR1 (0.53) | FFAR1FFAR4LMNAL3MBTL1 | |
| SCHEMBL4548366 | 0.81 | CA12 (0.49) | FFAR1FFAR4LMNAL3MBTL1 | |
| SCHEMBL3235704 | 0.78 | CYP1A2 (0.49) | FFAR1PPARDAKR1B1CYP4F2CYP4A11 | |
| SCHEMBL8008498 | 0.78 | RAB9A (0.50) | PPARGPPARA | |
| SCHEMBL1745370 | 0.78 | FFAR1 (1.00) | FFAR1FFAR4LMNAL3MBTL1AKR1B1 | |
| SCHEMBL27721793 | 0.77 | PPARA (0.39) | PPARGPPARACYP4F2CYP4A11 | |
| SCHEMBL1746780 | 0.77 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL6171029 | 0.75 | HDAC1 (0.41) | PPARGPPARA | |
| SCHEMBL8413352 | 0.75 | SIGMAR1 (0.44) | PPARGPPARACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098517-A1 | NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-09 | — | — | EP | disclosed |