Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434055 | 0.88 | TSHR (0.43) | TSHRNAMPTNLRP3ALDH1A1GAA | |
| SCHEMBL28068642 | 0.83 | KMT2A (0.39) | TSHRNAMPTNLRP3ACHEALDH1A1 | |
| SCHEMBL7387448 | 0.83 | ACHE (0.40) | TSHRNAMPTNLRP3ACHEALDH1A1 | |
| SCHEMBL289563 | 0.83 | CA1 (0.47) | ACHEALDH1A1CA12CA1CA2 | |
| SCHEMBL11048420 | 0.82 | ALDH1A1 (0.37) | TSHRNAMPTNLRP3ALDH1A1GAA | |
| SCHEMBL19335394 | 0.78 | NAMPT (0.41) | NAMPTALDH1A1AKR1B1CA12CA1 | |
| SCHEMBL15498947 | 0.77 | ELANE (0.38) | TSHRNAMPTALDH1A1GAACA12 | |
| SCHEMBL6060769 | 0.76 | CA1 (0.41) | NLRP3ACHEALDH1A1CA12CA1 | |
| SCHEMBL19028127 | 0.76 | SMN1; SMN2 (0.52) | TSHRNLRP3ALDH1A1GAAL3MBTL1 | |
| SCHEMBL2671806 | 0.76 | ACHE (0.47) | TSHRACHEALDH1A1GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905282-A | A kind of preparation method of benzo oxa- ring derivatives | 长沙深橙生物科技有限公司 | 2017-06-30 | — | — | CN | claimed |
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |
| EP-2595952-A1 | AGONISTS OF GPR40 | Connexios Life Sciences Pvt. Ltd. (IN) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |