Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.88 |
| ▸ | GPR3 | P46089 | 2/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.88 |
| ▸ | AHR | P35869 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL29355407 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL29627417 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL370524 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL30761795 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL7650 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL30209164 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL26134117 | 0.94 | ALDH1A1 (1.00) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL27863980 | 0.91 | ALDH1A1 (0.82) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL23782006 | 0.90 | ALDH1A1 (0.93) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL23148507 | 0.90 | ALDH1A1 (0.93) | ALDH1A1GPR3HSD17B10AHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | ALDH1A1 866/4885GPR3 3903/4885HSD17B10 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.