Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356473 | 0.85 | PTPN2 (0.43) | LMNAPIK3CATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4349922 | 0.85 | PTPN2 (0.43) | LMNAPIK3CATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4537918 | 0.85 | PTPN2 (0.43) | LMNAPIK3CATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL4353588 | 0.84 | PIK3CA (0.43) | LMNAPIK3CACYP2C9 | |
| SCHEMBL4347838 | 0.84 | NAMPT (0.44) | HRH3LMNAPIK3CASMN1; SMN2JAK2 | |
| SCHEMBL4358302 | 0.82 | PIK3CA (0.42) | HRH3PIK3CASMN1; SMN2 | |
| SCHEMBL4347963 | 0.81 | NPC1 (0.46) | LMNAHPGDPIK3CATSHRALDH1A1 | |
| SCHEMBL4355710 | 0.81 | KMT2A (0.47) | HRH3LMNAGAAHPGDSMN1; SMN2 | |
| SCHEMBL4533028 | 0.81 | HPGD (0.41) | HRH3HPGDPIK3CAALDH1A1JAK2 | |
| SCHEMBL4347925 | 0.80 | USP30 (0.40) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |