Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357683 | 0.90 | POLB (0.48) | HPGDL3MBTL3L3MBTL1ALDH1A1POLB | |
| SCHEMBL4351323 | 0.89 | HRH3 (0.45) | HPGDHRH3ALDH1A1 | |
| SCHEMBL4347885 | 0.88 | GPR119 (0.37) | HPGDPIK3CAALDH1A1KMT2APOLB | |
| SCHEMBL4540972 | 0.86 | GPR119 (0.47) | ABL1RIN1KMT2A | |
| SCHEMBL4540460 | 0.86 | SMN1; SMN2 (0.43) | HPGDPIK3CAALDH1A1 | |
| SCHEMBL4520212 | 0.86 | PTPN2 (0.47) | HPGDPIK3CAALDH1A1KMT2APOLB | |
| SCHEMBL4535866 | 0.86 | GPR119 (0.36) | PIK3CAHRH3 | |
| SCHEMBL4355595 | 0.84 | POLB (0.54) | HPGDALDH1A1POLB | |
| SCHEMBL13586029 | 0.83 | PTPN2 (0.44) | HPGDPIK3CAALDH1A1KMT2APOLB | |
| SCHEMBL4538463 | 0.83 | NPY2R (0.39) | ERN1HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |