Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536272 | 0.88 | KMT2A (0.43) | KMT2AACHEMEN1HPGDSMN1; SMN2 | |
| SCHEMBL4355595 | 0.84 | POLB (0.54) | ACHEALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4520212 | 0.84 | PTPN2 (0.47) | KMT2AALDH1A1LMNAMEN1HPGD | |
| SCHEMBL4538215 | 0.81 | PTPN2 (0.45) | KMT2AACHEALDH1A1LMNAMEN1 | |
| SCHEMBL13586060 | 0.81 | SMN1; SMN2 (0.47) | KMT2AACHEALDH1A1LMNAMEN1 | |
| SCHEMBL4349641 | 0.81 | HRH3 (0.47) | KMT2AGAAALDH1A1LMNAMEN1 | |
| SCHEMBL13586029 | 0.81 | PTPN2 (0.44) | KMT2AALDH1A1LMNAMEN1HPGD | |
| SCHEMBL13586043 | 0.81 | NPY2R (0.43) | KMT2AALDH1A1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL4357683 | 0.80 | POLB (0.48) | ALDH1A1HPGDSMN1; SMN2GRM5 | |
| SCHEMBL4537918 | 0.80 | PTPN2 (0.43) | ACHEALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |