Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354053 | 0.87 | TRPV1 (0.44) | TRPV1NAAAEPHX2 | |
| SCHEMBL4346130 | 0.85 | CA1 (0.51) | TRPV1NAAAEPHX2APPHSD17B10 | |
| SCHEMBL4356327 | 0.81 | TRPV1 (0.45) | TRPV1NAAAAPPHSD17B10MEN1 | |
| SCHEMBL4341744 | 0.79 | TRPV1 (0.46) | TRPV1MAPT | |
| SCHEMBL29178485 | 0.76 | L3MBTL1 (0.60) | TRPV1NAAAMEN1MAPTKMT2A | |
| SCHEMBL4350363 | 0.75 | TRPV1 (0.43) | TRPV1NAAA | |
| SCHEMBL4348484 | 0.75 | EPHX2 (0.43) | TRPV1NAAAEPHX2 | |
| SCHEMBL4355852 | 0.74 | EPHX2 (0.48) | TRPV1NAAAEPHX2 | |
| SCHEMBL4350070 | 0.74 | NAAA (0.40) | TRPV1NAAAEPHX2 | |
| SCHEMBL4346809 | 0.74 | TRPV1 (0.46) | TRPV1NAAAEPHX2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | disclosed |