Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.42 |
| ▸ | NAAA | Q02083 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350102 | 0.87 | TRPV1 (0.49) | TRPV1EPHX2NAAA | |
| SCHEMBL4350363 | 0.84 | TRPV1 (0.43) | TRPV1EPHX1NAAAASAH1 | |
| SCHEMBL4348484 | 0.84 | EPHX2 (0.43) | TRPV1EPHX2EPHX1NAAA | |
| SCHEMBL4349401 | 0.80 | MGLL (0.38) | TRPV1EPHX2EPHX1NAAALMNA | |
| SCHEMBL4350070 | 0.79 | NAAA (0.40) | TRPV1EPHX2EPHX1NAAASMN1; SMN2 | |
| SCHEMBL4355852 | 0.79 | EPHX2 (0.48) | TRPV1EPHX2EPHX1NAAALMNA | |
| SCHEMBL4351425 | 0.76 | EPHX2 (0.37) | TRPV1EPHX2EPHX1NAAA | |
| SCHEMBL4346130 | 0.76 | CA1 (0.51) | TRPV1EPHX2EPHX1NAAA | |
| SCHEMBL4349030 | 0.75 | RAB9A (0.49) | TRPV1EPHX1 | |
| SCHEMBL4358550 | 0.74 | EPHX2 (0.39) | TRPV1EPHX2EPHX1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | claimed |
| EP-2100876-A2 | New compounds for the inhibition of rotamases and use thereof | Jerini AG (DE) | 2009-09-16 | — | — | EP | disclosed |