SCHEMBL4350348

SCHEMBL4350348

C=CCCCOc1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HTT P42858 3/20 0.66
PKM P14618 1/20 0.61
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
PLA2G4B P0C869 4/20 0.57
MAPK1 P28482 2/20 0.54
RARB P10826 4/20 0.54
POLB P06746 1/20 0.54
APEX1 P27695 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MAPT P10636 1/20 0.53
USP2 O75604 1/20 0.51
ALOX15 P16050 1/20 0.51
HSD17B10 Q99714 1/20 0.51
PLA2G4A P47712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940429 0.95 ALDH1A1 (0.91) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL1871410 0.95 ALDH1A1 (0.90) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL13346213 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL4353031 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL2622416 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL8379459 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL9448865 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
Hydrochloric Acid SCHEMBL8152259 0.93 ALDH1A1 (0.88) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL3313611 0.91 ALDH1A1 (0.84) ALDH1A1L3MBTL1HTTPKMTSHR
SCHEMBL8175158 0.91 ALDH1A1 (0.82) ALDH1A1L3MBTL1HTTPKMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11391526-B2 Heat-transmitting modifier for elastomer, heat-transmission-modified crystalline elastomer, method for using crystalline polymer and precursor thereof, method for heat-transmission modification of elastomer, heater body, and heated body I.S.T CORPORATION (JP) 2022-07-19 US claimed
US-6342592-B1 FUNCTIONALIZED ALKENOXYARYL OR ALKENYLARYLOXYARYL COMPOUND; SEPARATING ENANTIOMORPHS USING THREE-DIMENSIONAL NETWORKS; CHROMATOGRAPHY INSTITUT FRANCAIS DU PETROLE AND CHIRALSEP (FR) 2002-01-29 US claimed
US-11391526-B2 Heat-transmitting modifier for elastomer, heat-transmission-modified crystalline elastomer, method for using crystalline polymer and precursor thereof, method for heat-transmission modification of elastomer, heater body, and heated body I.S.T CORPORATION (JP) 2022-07-19 US disclosed
US-7576034-B2 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2009-08-18 US disclosed
US-7230123-B2 Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups COMMISSARIAT A L'ENERGIR ATOMIQUE (FR) 2007-06-12 US disclosed
US-7067640-B1 Cross-linked chiral compounds and methods of making thereof EKA CHEMICALS AB (SE) 2006-06-27 US disclosed
US-20050143587-A1 Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2005-06-30 US disclosed
US-20040260081-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof EKA CHEMICALS AB (SE) 2004-12-23 US disclosed
US-6342592-B1 FUNCTIONALIZED ALKENOXYARYL OR ALKENYLARYLOXYARYL COMPOUND; SEPARATING ENANTIOMORPHS USING THREE-DIMENSIONAL NETWORKS; CHROMATOGRAPHY INSTITUT FRANCAIS DU PETROLE AND CHIRALSEP (FR) 2002-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040260081-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof MTCL3, OR10J3, MCM4 ALDH1A1 2168/4885L3MBTL1 4720/4885HTT 1105/4885
US-20050143587-A1 Ureido or carbamate derivatives of crown ethers and of silicon usable for preparing supports intended for the separation by chromatography of metal cations and of organic molecules comprising amine functional groups UTS2R, SRM, SMOX ALDH1A1 3701/4885L3MBTL1 4661/4885HTT 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.