Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729260 | 0.82 | TDP1 (0.50) | TDP1L3MBTL1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19664179 | 0.80 | TSHR (0.45) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL23859898 | 0.76 | ALDH1A1 (0.49) | TSHRALDH1A1HSD17B10LMNAMAPK1 | |
| SCHEMBL14634258 | 0.76 | GRIA2 (0.50) | ESR1TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL23859867 | 0.76 | ALDH1A1 (0.49) | TSHRALDH1A1HSD17B10LMNAMAPK1 | |
| SCHEMBL2734875 | 0.76 | ALPI (0.54) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL216480 | 0.76 | ALPI (0.54) | TSHRTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL17773504 | 0.75 | PPARG (0.46) | IAPPTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL30883294 | 0.75 | IAPP (0.46) | IAPPTDP1L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL157790 | 0.75 | KDM4E (0.56) | IAPPTSHRTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | ELLNEUROXX LTD. (DE) | 2009-11-19 | — | — | US | disclosed |
| EP-1879880-A2 | DIHYDROXYPHENYLALANINE DERIVATIVES | Ellneuroxx Ltd. (DE) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119758-A2 | DIHYDROXYPHENYLALANINE DERIVATIVES | ELLNEUROXX LTD. (DE) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285888-A1 | DERIVATIVES OF DIHYDROXYPHENYLALANINE | HTT, NLN, SNCA | IAPP 892/4885ESR1 4385/4885TSHR 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.