Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350641 | 0.82 | IAPP (0.48) | TDP1LMNASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL1893385 | 0.78 | SLC7A5 (0.55) | TDP1SLC7A5LMNASERPINE1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11029830 | 0.74 | USP2 (0.46) | TDP1TYRLMNACYBBPPARG | |
| SCHEMBL157790 | 0.74 | KDM4E (0.56) | TDP1SLC7A5LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL1700767 | 0.74 | KDM4E (0.56) | TDP1SLC7A5LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29540097 | 0.74 | KDM4E (0.56) | TDP1SLC7A5LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL416566 | 0.73 | TDP1 (0.91) | TDP1LMNASERPINE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8679047 | 0.73 | TDP1 (0.66) | TDP1TYRLMNAL3MBTL1 | |
| SCHEMBL14095409 | 0.71 | ALPI (0.61) | SLC7A5LMNA | |
| SCHEMBL30883294 | 0.71 | IAPP (0.46) | TDP1LMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008034087-A2 | TREATING SCHIZOPHRENIA WITH COMBINATIONS OF LEVODOPA AND AN ANTIPSYCHOTIC AGENT | XENOPORT, INC. (US) | 2008-03-20 | — | — | WO | disclosed |