⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28658095 | 0.85 | ALDH1A1 (0.38) | — | |
| SCHEMBL31737439 | 0.83 | ALDH5A1 (0.46) | — | |
| Flurothyl SCHEMBL28708358 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL18656115 | 0.76 | — | — | |
| SCHEMBL1356310 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL7800455 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL31607175 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL30895180 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL31607177 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL31607172 | 0.73 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563765-B | Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant | 青岛玉城科技有限公司 | 2022-01-14 | — | — | CN | claimed |
| WO-2021013419-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2021-01-28 | — | — | WO | claimed |
| CN-110563765-A | Synthesis method of Schiff base phosphazene double-base structure flame retardant and modified polyurethane flame retardant | 青岛玉城科技有限公司 | 2019-12-13 | — | — | CN | claimed |
| US-20140309192-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC, | 2014-10-16 | — | — | US | claimed |
| CN-104105691-A | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC | 2014-10-15 | — | — | CN | claimed |
| EP-2776407-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2014-09-17 | — | — | EP | claimed |
| WO-2013070657-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| US-8309578-B2 | Bicyclic pyrazole and isoxazole derivatives as antitumor and antineurodegenerative agents | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-11-13 | — | — | US | claimed |
| CN-101845091-A | Metastin derivative and use thereof | TAKEDA PHARMACEUTICAL | 2010-09-29 | — | — | CN | claimed |
| US-20070203138-A1 | Novel Compounds and Compositions as Cathepsin S Inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-08-30 | — | — | US | claimed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | claimed |
| WO-2003042197-A1 | OLIGOPEPTIDES AND COMPOSITIONS CONTAINING THEM AS CATHEPSIN S INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-05-22 | — | — | WO | claimed |
| WO-2003024924-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2003-03-27 | — | — | WO | claimed |
| WO-2003024923-A1 | SULFONAMIDE COMPOUNDS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | claimed |
| JP-2002539201-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| EP-1063235-A1 | BENZOFURYLPYRONE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-12-27 | — | — | EP | claimed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | claimed |
| EP-0569947-B1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1995-03-01 | — | — | EP | claimed |