Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL4870461 | 0.92 | BCHE (0.34) | BCHEACHELMNAALDH1A1KDM4E | |
| SCHEMBL4635239 | 0.87 | HTR1A (0.38) | BCHEACHELMNAALDH1A1KDM4E | |
| Sulfuric Acid SCHEMBL30128115 | 0.83 | ALDH1A1 (0.46) | LMNAALDH1A1KDM4EELANEMAPT | |
| Methacrylic Acid SCHEMBL4870456 | 0.83 | ELANE (0.32) | ALDH1A1KDM4EELANETSHR | |
| SCHEMBL5576290 | 0.78 | ELANE (0.46) | BCHEACHELMNAALDH1A1ELANE | |
| SCHEMBL5069672 | 0.77 | HTR1A (0.39) | BCHEACHELMNAALDH1A1KDM4E | |
| SCHEMBL29405469 | 0.76 | ELANE (0.54) | BCHEACHEALDH1A1ELANEMAPT | |
| Sulfuric Acid SCHEMBL597318 | 0.75 | TSHR (0.41) | LMNAALDH1A1KDM4EMAPTHPGD | |
| Sulfuric Acid SCHEMBL482693 | 0.75 | CA12 (0.36) | LMNAALDH1A1RAB9ATSHRNPC1 | |
| SCHEMBL4368552 | 0.74 | ELANE (0.38) | BCHEACHELMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090033859-A1 | Liquid Crystal Spacer, Spacer Diffusion Liquid, Liquid Crystal Display Device Manufacturing Method, and Liquid Crystal Display Device | SEKISUI CHEMICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-7470416-B2 | Conductive fine particles and anisotropic conductive material | SEKISUI CHEMICAL CO., LTD. (JP) | 2008-12-30 | — | — | US | disclosed |
| US-20070281161-A1 | Conductive Fine Particles And Anisotropic Conductive Material | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-12-06 | — | — | US | disclosed |
| US-7291393-B2 | Coated conductive particle coated conductive particle manufacturing method anisotropic conductive material and conductive connection structure | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20060154070-A1 | Coated conductive particle coated conductive particle manufacturing method anisotropic conductive material and conductive connection structure | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1426979-A1 | COATED CONDUCTIVE PARTICLE, COATED CONDUCTIVE PARTICLE MANUFACTURING METHOD, ANISOTROPIC CONDUCTIVE MATERIAL, AND CONDUCTIVE CONNECTION STRUCTURE | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-09 | — | — | EP | disclosed |