Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345839 | 0.87 | AVPR1A (0.33) | GAAALDH1A1 | |
| SCHEMBL4346468 | 0.76 | GAA (0.41) | GAAALDH1A1TSHRKMT2A | |
| SCHEMBL4341694 | 0.64 | HPGD (0.42) | GAAALDH1A1TSHRKMT2A | |
| SCHEMBL4347434 | 0.63 | GAA (0.48) | GAAALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL4351639 | 0.60 | HPGD (0.59) | GAAALDH1A1MAPTTSHR | |
| SCHEMBL4354898 | 0.59 | GAA (0.40) | GAAALDH1A1 | |
| SCHEMBL1856622 | 0.57 | THRB (0.39) | ALDH1A1 | |
| SCHEMBL3399484 | 0.56 | POLB (0.45) | GAAALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL4352206 | 0.56 | GAA (0.39) | GAAALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL31085036 | 0.55 | ALDH1A1 (0.39) | ALDH1A1TSHRKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |