⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351251 | 0.78 | — | — | |
| SCHEMBL12961895 | 0.76 | — | — | |
| SCHEMBL8255191 | 0.76 | — | — | |
| SCHEMBL1749889 | 0.76 | — | — | |
| SCHEMBL2759533 | 0.76 | — | — | |
| SCHEMBL13419141 | 0.76 | — | — | |
| SCHEMBL351473 | 0.75 | LOXL2 (0.46) | — | |
| SCHEMBL318570 | 0.73 | — | — | |
| SCHEMBL2642671 | 0.73 | LOXL2 (0.44) | — | |
| SCHEMBL29911003 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201282-A1 | NOVEL GSPT1 COMPOUNDS AND METHODS OF USE OF THE NOVEL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-19 | — | — | WO | disclosed |
| WO-2020207352-A1 | TRIAZINE BENZIMIDAZOLE COMPOUNDS AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-10-15 | — | — | WO | disclosed |
| EP-1961733-B1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-08-20 | — | — | EP | disclosed |
| CN-101370765-B | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO | 2013-03-13 | — | — | CN | disclosed |
| US-8269044-B2 | Method for selectively producing primary amine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-18 | — | — | US | disclosed |
| WO-2010105960-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010070300-A2 | FUNCTIONALISING REAGENTS AND THEIR USES | THE UNIVERSITY OF BATH (GB) | 2010-06-24 | — | — | WO | disclosed |
| US-20090281325-A1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-12 | — | — | US | disclosed |
| CN-101370765-A | Method for selectively producing primary amine | SUMITOMO CHEMICAL CO (JP) | 2009-02-18 | — | — | CN | disclosed |
| EP-1961733-A1 | METHOD FOR SELECTIVELY PRODUCING PRIMARY AMINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-08-27 | — | — | EP | disclosed |