⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037897 | 0.82 | CA2 (0.43) | — | |
| SCHEMBL20255474 | 0.79 | LTA4H (0.43) | — | |
| SCHEMBL4351251 | 0.78 | — | — | |
| SCHEMBL20255476 | 0.77 | CA2 (0.41) | — | |
| SCHEMBL12961895 | 0.76 | — | — | |
| SCHEMBL2759533 | 0.76 | — | — | |
| SCHEMBL8255191 | 0.76 | — | — | |
| SCHEMBL13419141 | 0.76 | — | — | |
| SCHEMBL4351240 | 0.76 | — | — | |
| SCHEMBL2994079 | 0.74 | GABRP (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108456163-A | Compound and its preparation method and application containing adjacent amino heteroaryl cycloalkynyl radical | 中国科学院上海药物研究所 | 2018-08-28 | — | — | CN | disclosed |
| EP-2356113-B1 | HETEROCYCLICALLY SUBSTITUTED ARYL COMPOUNDS AS HIF INHIBITORS | BAYER IP GMBH (DE) | 2015-01-07 | — | — | EP | disclosed |
| US-20130196964-A1 | HETEROCYCLICALLY SUBSTITUTED ARYL COMPOUNDS AS HIF INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2013-08-01 | — | — | US | disclosed |
| US-8383652-B2 | Biaromatic compounds that modulate PPAR-receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-02-26 | — | — | US | disclosed |
| US-20110312930-A1 | Aryl compounds with aminoalkyl substituents and their use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-22 | — | — | US | disclosed |
| CN-102282142-A | Substituted aryl compounds and their use | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110301122-A1 | HETEROAROMATIC COMPOUNDS FOR USE AS HIF INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-08 | — | — | US | disclosed |
| US-8022079-B2 | Methods of modulating PPAR gamma-type receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-09-20 | — | — | US | disclosed |
| EP-1638964-B1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-07-27 | — | — | EP | disclosed |
| US-7968560-B2 | Compounds that modulate PPARγ-type receptors and cosmetic/pharmaceutical compositions comprising said compounds | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-28 | — | — | US | disclosed |
| US-20060148862-A1 | Novel compounds that modulate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-07-06 | — | — | US | disclosed |
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |
| EP-0302346-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| CN-1022563-C | Pyridazinone derivatives for controlling preventing pests | NISSAN CHEMICAL IND LTD (JP) | 1993-10-27 | — | — | CN | disclosed |
| CN-1062636-A | Be used for control (or) pyridazinone derivative and the composition of pre-pest control | NISSAN CHEMICAL IND LTD (JP) | 1992-07-15 | — | — | CN | disclosed |
| US-4945091-A | INSECTICIDES, ACARACIDES, NEMATOCIDES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-31 | — | — | US | disclosed |
| US-4910201-A | With an ether substituted in position 5 | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0302346-A2 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |
| CN-1030913-A | Pyridazinone derivatives and compositions for controlling preventing pests | NISSAN CHEMICAL IND LTD (JP) | 1989-02-08 | — | — | CN | disclosed |