SCHEMBL43513

SCHEMBL43513

CC(Nc1ccco1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
PTPN1 P18031 2/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
PTPN7 P35236 1/20 0.46
BLM P54132 1/20 0.46
ESR2 Q92731 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.41
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4595894 1.00 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
SCHEMBL43514 1.00 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
Gamma-Aminobutyric Acid SCHEMBL2770343 0.84 KMT2A (0.41) KMT2APTPN1POLBPKMPTPN7
SCHEMBL29747049 0.81 KMT2A (0.43) KMT2APTPN1POLBPKMPTPN7
SCHEMBL29747363 0.80 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
Hydrochloric Acid SCHEMBL9473668 0.80 ALDH1A1 (0.51) KMT2APOLBL3MBTL1SMN1; SMN2ALOX5
Hydrochloric Acid SCHEMBL9473673 0.80 ALDH1A1 (0.51) KMT2APOLBL3MBTL1SMN1; SMN2ALOX5
SCHEMBL19463110 0.80 KDM4E (0.39) POLBSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9955771 0.78 MME (0.43) POLBL3MBTL1ALDH1A1MAPT
SCHEMBL9955768 0.78 MME (0.43) POLBL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358948-B2 Neurotensinergic agonists and methods of using same preventing or treating pain SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2025-07-15 US claimed
EP-3912641-B1 HYDROPHILIC DRUG-LINKER COMPOUNDS SEAGEN INC (US) 2024-11-06 EP claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 EP claimed
US-20240108738-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2024-04-04 US claimed
WO-2024030977-A2 NOVEL MELANOCORTIN ANALOGS SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) 2024-02-08 WO claimed
CN-117529489-A Bicyclic peptide ligands specific for NK cells 拜斯科技术开发有限公司 2024-02-06 CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 EP claimed
US-20230132738-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2023-05-04 US claimed
US-20230021419-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR IL-17 BICYCLETX LIMITED (GB) 2023-01-26 US claimed
US-11510959-B2 Hydrophilic antibody-drug conjugates SEAGEN INC. (US) 2022-11-29 US claimed
US-20070027091-A1 Novel Melanocortin Receptor Agonists NOVO NORDISK A/S (DK) 2007-02-01 US claimed
WO-2007009894-A2 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2007-01-25 WO claimed
WO-2006108818-A2 TRIMERIC PEPTIDES FOR USE IN TREATING OBESITY NOVO NORDISK A/S (DK) 2006-10-19 WO claimed
EP-1670815-A2 MELANOCORTIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2006-06-21 EP claimed
WO-2006048452-A2 PEPTIDES FOR USE IN TREATING OF OBESITY NOVO NORDISK A/S (DK) 2006-05-11 WO claimed
WO-2006048451-A1 PEPTIDES FOR USE IN THE TREATMENT OF OBESITY NOVO NORDISK A/S (DK) 2006-05-11 WO claimed
EP-1625158-A2 PEPTIDES FOR USE IN TREATING OBESITY NOVO NORDISK A/S (DK) 2006-02-15 EP claimed
WO-2005030797-A2 MELANOCORTIN RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2005-04-07 WO claimed
WO-2004099246-A2 PEPTIDES FOR USE IN TREATING OBESITY NOVO NORDISK A/S (DK) 2004-11-18 WO claimed
US-6566338-B1 Administering caspase inhibitor for therapy of oral mucositis, gastrointestinal mucositis, bladder mucositis or proctitis resulting from chemotherapy or radiation therapy of cancer in an animal CYTOVIA, INC. 2003-05-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11510959-B2 Hydrophilic antibody-drug conjugates CD44, FCGR1A, FCGR2A KMT2A 1371/4885PTPN1 3862/4885POLB 4239/4885
US-20070027091-A1 Novel Melanocortin Receptor Agonists MC4R, MC3R, MC5R KMT2A 3423/4885PTPN1 1041/4885POLB 3655/4885
US-20240108738-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS PBK, KLRK1, MICA KMT2A 1977/4885PTPN1 2190/4885POLB 4155/4885
US-20230021419-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR IL-17 IL17A, IL23R, IL15 KMT2A 4302/4885PTPN1 1456/4885POLB 4432/4885
US-12358948-B2 Neurotensinergic agonists and methods of using same preventing or treating pain VIP, NTSR2, VIPR2 KMT2A 3715/4885PTPN1 3670/4885POLB 4202/4885
US-20230132738-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES CD44, FCGR1A, FCGR2A KMT2A 1371/4885PTPN1 3862/4885POLB 4239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.