SCHEMBL4595894

SCHEMBL4595894

C[C@@H](Nc1ccco1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
PTPN1 P18031 2/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
PTPN7 P35236 1/20 0.46
BLM P54132 1/20 0.46
ESR2 Q92731 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.41
ALOX5 P09917 1/20 0.39
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
KDM4C Q9H3R0 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43513 1.00 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
SCHEMBL43514 1.00 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
Gamma-Aminobutyric Acid SCHEMBL2770343 0.84 KMT2A (0.41) KMT2APTPN1POLBPKMPTPN7
SCHEMBL29747049 0.81 KMT2A (0.43) KMT2APTPN1POLBPKMPTPN7
SCHEMBL29747363 0.80 KMT2A (0.46) KMT2APTPN1POLBPKMPTPN7
Hydrochloric Acid SCHEMBL9473668 0.80 ALDH1A1 (0.51) KMT2APOLBL3MBTL1SMN1; SMN2ALOX5
Hydrochloric Acid SCHEMBL9473673 0.80 ALDH1A1 (0.51) KMT2APOLBL3MBTL1SMN1; SMN2ALOX5
SCHEMBL19463110 0.80 KDM4E (0.39) POLBSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9955771 0.78 MME (0.43) POLBL3MBTL1ALDH1A1MAPT
SCHEMBL9955768 0.78 MME (0.43) POLBL3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9434764-B2 Skin care compositions and methods comprising selective agonists of melanocortin 1 receptor UNIVERSITY OF CINCINNATI (US) 2016-09-06 US claimed
US-20150297667-A1 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-10-22 US claimed
US-20150299251-A1 Skin Care Compositions and Methods Comprising Selective Agonists of Melanocortin 1 Receptor UNIVERSITY OF CINCINNATI (US) 2015-10-22 US claimed
EP-2925340-A2 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR University Of Cincinnati (US) 2015-10-07 EP claimed
EP-2922565-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR University Of Cincinnati (US) 2015-09-30 EP claimed
WO-2014081846-A2 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO claimed
WO-2014081845-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO claimed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
EP-4545553-A2 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND ShangPharma Innovation Inc. (US) 2025-04-30 EP disclosed
WO-2025079064-A1 INTERLEUKIN-17 PEPTIDOMIMETIC INHIBITORS PEPTICOM LTD. (IL) 2025-04-17 WO disclosed
US-11981753-B2 Peptide compound and application thereof, and composition containing peptide compound SHANGPHARMA INNOVATION INC. (US) 2024-05-14 US disclosed
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2023-11-07 US disclosed
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2022-08-30 US disclosed
EP-2922565-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR University Of Cincinnati (US) 2015-09-30 EP disclosed
WO-2014081846-A2 PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC METHODS OF USE COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO disclosed
WO-2014081845-A2 SKIN CARE COMPOSITIONS AND METHODS COMPRISING SELECTIVE AGONISTS OF MELANOCORTIN 1 RECEPTOR UNIVERSITY OF CINCINNATI (US) 2014-05-30 WO disclosed
EP-1874768-A2 INHIBITORS OF AKT ACTIVITY SMITHKLINE BEECHAM CORPORATION (US) 2008-01-09 EP disclosed
WO-2006113837-A2 INHIBITORS OF AKT ACTIVITY SMITHKLINE BEECHAM CORPORATION (US) 2006-10-26 WO disclosed
EP-1121446-A1 AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS Chirotech Technology Limited (GB) 2001-08-08 EP disclosed
WO-2000023598-A1 AMINOACYLASE AND ITS USE IN THE PRODUCTION OF D-AMINOACIDS CHIROTECH TECHNOLOGY LIMITED (GB) 2000-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981753-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, NPY1R, GLP1R KMT2A 1451/4885PTPN1 400/4885POLB 4008/4885
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, NPY1R KMT2A 3979/4885PTPN1 1347/4885POLB 4665/4885
US-11807660-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, SSTR3 KMT2A 1706/4885PTPN1 1521/4885POLB 4638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.