SCHEMBL4351346

SCHEMBL4351346

O=C(O)c1ccc(O)cc1Cc1ccccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
HTT P42858 1/20 0.50
NR4A2 P43354 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
MCL1 Q07820 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HMGB1 P09429 1/20 0.44
CXCL12 P48061 1/20 0.44
MEN1 O00255 1/20 0.44
EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389870 0.85 ALDH1A1 (0.59) ALDH1A1CA12CA1CA2TSHR
SCHEMBL5455142 0.83 ALDH1A1 (0.61) TP53HTTNR4A2NPC1RAB9A
SCHEMBL8767646 0.81 HTT (0.47) HTTALDH1A1MCL1CA12CA1
SCHEMBL310681 0.80 PTPN1 (0.58) ALDH1A1CA12CA1CA2TSHR
SCHEMBL10767990 0.78 HSD17B10 (0.46) HSP90AA1MEN1MAPTKMT2ACAMK2A
SCHEMBL11327561 0.78 HMGB1 (0.54) TP53HTTALDH1A1MCL1TSHR
(Chloromethyl)Benzene SCHEMBL7198605 0.77 PTPN1 (0.51) ALDH1A1CA12CA1CA2TSHR
SCHEMBL3442800 0.76 MEN1 (0.58) NR4A2NPC1RAB9AALDH1A1CA12
SCHEMBL10599031 0.76 PTPN1 (0.49) ALDH1A1CA12CA1CA2TSHR
SCHEMBL27212833 0.75 ALOX5 (0.59) ALDH1A1HSP90AA1MEN1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102019782-B Thermosensitive recording material and production method thereof RICOH CO LTD 2013-11-06 CN disclosed
CN-102019782-A Thermosensitive recording material and production method thereof RICOH CO LTD 2011-04-20 CN disclosed
US-7476448-B2 Coating paper which can be removed by water and a method for preparation thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2009-01-13 US disclosed
US-20060216537-A1 Coating paper which can be removed by water and a method for preparation thereof NIPPON PAPER PAPYLIA CO., LTD. (JP) 2006-09-28 US disclosed
EP-1705288-A2 A coating paper which can be removed by water and a method for preparation thereof Nippon Paper Industries Co., Ltd. (JP) 2006-09-27 EP disclosed
EP-0596224-B1 Heat-sensitive recording material MITSUI CHEMICALS INC (JP) 1999-01-13 EP disclosed
US-5476957-A Dye for heat sensitive recording MITSUI TOATSU CHEMICALS, INC. (JP) 1995-12-19 US disclosed
US-5346878-A Preservation stability of white portions and images MITSUI TOATSU CHEMICALS, INC. (JP) 1994-09-13 US disclosed
EP-0596224-A2 Heat-sensitive recording material MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-05-11 EP disclosed
US-4727162-A COLOR FORMERS FOR HEAT OR PRESSURE RECORDING MATERIAL SHIN NISSO KAKO CO., LTD. (JP) 1988-02-23 US disclosed
US-4695640-A COLOR FORMER FOR RECORDING MATERIALS SHIN NISSO KAKO CO., LTD. (JP) 1987-09-22 US disclosed