SCHEMBL4351591

SCHEMBL4351591

O=C1CC2CCC(C1)N2CO

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7804376 0.79 MAPK1 (0.41) MAPK1MEN1KMT2A
SCHEMBL5071115 0.76 MAPK1 (0.46) MAPK1MEN1KMT2A
SCHEMBL7647959 0.76 SMN1; SMN2 (0.38) MAPK1MEN1KMT2A
SCHEMBL28641227 0.73 MAPK1 (0.43) MAPK1MEN1KMT2A
SCHEMBL5415021 0.73 MAPK1 (0.48) MAPK1MEN1KMT2A
SCHEMBL18153764 0.72 MAPK1 (0.46) MAPK1MEN1KMT2A
SCHEMBL6573342 0.71 MAPK1 (0.42) MAPK1MEN1KMT2A
SCHEMBL4820734 0.71 OPRM1 (0.41) MAPK1
SCHEMBL5965398 0.71 AR (0.38) MAPK1MEN1KMT2A
SCHEMBL1010815 0.70 BRD4 (0.39) MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090285919-A1 Rice Bran Extracts for Inflammation and Methods of Use Thereof HALPERN, BARUCH 2009-11-19 US disclosed
WO-2008156654-A2 CYTOSKELETON MODULATORS FOR TREATING METABOLIC DISORDERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-12-24 WO disclosed
US-20080160116-A1 Compositions and Methods Comprising Zingiber Species HERBALSCIENCE SINGAPORE PTE. LTD (SG) 2008-07-03 US disclosed
EP-0911153-B1 Image forming method KONISHIROKU PHOTO IND (JP) 2003-12-10 EP disclosed
US-6174646-B1 IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION KONICA CORPORATION (JP) 2001-01-16 US disclosed
EP-0911153-A1 Image forming method KONICA CORPORATION (JP) 1999-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160116-A1 Compositions and Methods Comprising Zingiber Species AGL, SQLE, RBPJ MAPK1 2950/4885MEN1 4372/4885KMT2A 2849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.