Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799242 | 0.92 | MAPK1 (0.38) | MAPK1TSHRUSP2HTTHSD17B10 | |
| SCHEMBL4351591 | 0.79 | MAPK1 (0.41) | MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7805841 | 0.76 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL28641227 | 0.75 | MAPK1 (0.43) | MAPK1KMT2AMEN1 | |
| SCHEMBL5415021 | 0.75 | MAPK1 (0.48) | MAPK1KMT2AMEN1SIGMAR1ALDH1A1 | |
| SCHEMBL7799394 | 0.73 | OPRM1 (0.31) | TSHRUSP2HTTHSD17B10SIGMAR1 | |
| SCHEMBL7808200 | 0.73 | OPRM1 (0.31) | TSHRUSP2HTTHSD17B10SIGMAR1 | |
| SCHEMBL25993195 | 0.72 | KDM4E (0.37) | SMYD3 | |
| Hydrochloric Acid SCHEMBL8389564 | 0.72 | DRD2 (0.31) | MAPK1KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL24114565 | 0.71 | LMNA (0.48) | TSHRUSP2HTTHSD17B10SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11029571-A | — | — | None | — | — | JP | disclosed |
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| JP-H1129571-A | PRODUCTION OF ENDO-8-SUBSTITUTED-3-AMINO-8-AZABICYCLO(3.2.1)OCTANE DERIVATIVE | TAISHO PHARMACEUT CO LTD | 1999-02-02 | — | — | JP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | KRAS, NRAS, BRAF | MAPK1 81/4885TSHR 4687/4885USP2 3463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.