Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479332 | 0.82 | MAP3K14 (0.50) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL29956517 | 0.81 | MAP3K14 (0.41) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL29129779 | 0.78 | MAP3K14 (0.46) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL28520632 | 0.76 | MAP3K14 (0.44) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL3042782 | 0.75 | FAAH (0.44) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL23199745 | 0.74 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL1536267 | 0.74 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL1056468 | 0.74 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL1838214 | 0.74 | MAP3K14 (0.43) | MAP3K14GLACRBNDDB1FFAR1 | |
| SCHEMBL10573688 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009082129-A | PROCESS FOR PREPARING CHIRAL COMPOUND | PFIZER PROD INC | 2009-04-23 | — | — | JP | disclosed |