Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25575102 | 0.90 | GRIK1 (0.42) | GRIK1GRIK2 | |
| SCHEMBL11257659 | 0.85 | GRIK1 (0.31) | GRIK1GRIK2 | |
| SCHEMBL8808086 | 0.82 | ACHE (0.34) | — | |
| SCHEMBL9023602 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL3092130 | 0.77 | GRIK1 (0.48) | GRIK1GRIK2 | |
| SCHEMBL2759245 | 0.76 | — | — | |
| SCHEMBL14950815 | 0.76 | — | — | |
| SCHEMBL7706660 | 0.76 | — | — | |
| SCHEMBL7550733 | 0.75 | GRIK1 (0.39) | GRIK1GRIK2 | |
| SCHEMBL13864226 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170259099-A1 | SILICON-CONTAINING ORGANIC ACID DERIVATIVES AS ENVIRONMENTALLY FRIENDLY AFFF EXTINGUISHING AGENTS | UNIVERSITÄT ZU KÖLN (DE) | 2017-09-14 | — | — | US | disclosed |
| US-9260473-B2 | Bivalent multifunctional ligands targeting Aβ oligomers as treatment for Alzheimer's disease | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-9260473-B2 | Bivalent multifunctional ligands targeting Aβ oligomers as treatment for Alzheimer's disease | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-9260473-B2 | Bivalent multifunctional ligands targeting Aβ oligomers as treatment for Alzheimer's disease | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2016-02-16 | — | — | US | disclosed |
| US-20130156705-A1 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING A[BETA] OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130156705-A1 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING A[BETA] OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130156705-A1 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING A[BETA] OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2012076696-A1 | NEW METAL CARBONYL COMPLEXES OF CURCUMIN DERIVATIVES, THEIR SYNTHESIS AND THEIR USES IN THERAPEUTIC APPLICATION | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012012257-A2 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING Aβ OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012012257-A2 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING Aβ OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156705-A1 | BIVALENT MULTIFUNCTIONAL LIGANDS TARGETING A[BETA] OLIGOMERS AS TREATMENT FOR ALZHEIMER'S DISEASE | LDLR, NR1H2, MSR1 | GRIK1 1089/4885GRIK2 662/4885SLC6A2 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.