Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.58 |
| ▸ | THRB | P10828 | 12/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4931010 | 0.91 | THRA (0.48) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL4934663 | 0.89 | THRA (0.59) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL4532725 | 0.88 | THRB (0.74) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL4929660 | 0.88 | THRA (0.51) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL4355861 | 0.88 | THRB (0.44) | THRATHRB | |
| SCHEMBL4932877 | 0.87 | THRA (0.57) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL5120011 | 0.86 | THRA (0.47) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL5111376 | 0.86 | THRA (0.49) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL4934426 | 0.86 | THRA (0.45) | THRATHRBFFAR4FFAR1ESR1 | |
| SCHEMBL5116865 | 0.85 | THRA (0.47) | THRATHRBFFAR4FFAR1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | claimed |
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |
| US-20080221210-A1 | Thyroid Receptor Agonists | KARO BIO AB (SE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221210-A1 | Thyroid Receptor Agonists | TSHR, TRHR, THRA | THRA 3/4885THRB 4/4885FFAR4 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.