Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PDE9A | O76083 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128417 | 0.91 | CYP3A4 (0.60) | CYP3A4FLT3KDM4ESLC2A1SLC2A2 | |
| SCHEMBL4366581 | 0.90 | CYP3A4 (0.56) | CYP3A4FLT3RAB9AKDM4ENPC1 | |
| SCHEMBL4360972 | 0.90 | CYP3A4 (0.60) | CYP3A4FLT3RAB9ANPC1CYP2C9 | |
| SCHEMBL4355637 | 0.90 | CYP3A4 (0.60) | CYP3A4FLT3KDM4EPDE9ACYP2C9 | |
| SCHEMBL4354583 | 0.90 | CYP3A4 (0.60) | CYP3A4FLT3KDRCYP2C9MAPT | |
| SCHEMBL4358437 | 0.88 | CYP3A4 (0.59) | CYP3A4FLT3POLBRAB9AKDM4E | |
| SCHEMBL2019784 | 0.88 | CYP3A4 (0.79) | CYP3A4CYP2C9 | |
| SCHEMBL4356756 | 0.88 | CYP3A4 (0.61) | CYP3A4FLT3CYP2C9BTK | |
| SCHEMBL4353817 | 0.88 | CYP3A4 (0.58) | CYP3A4FLT3CYP2C9BTK | |
| SCHEMBL1128343 | 0.88 | CYP3A4 (0.81) | CYP3A4CYP2C9ALDH1A1SRCTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188098-B2 | GPR119 receptor agonists | HOFFMANN-LA ROCHE INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090286812-A1 | GPR119 Receptor Agonists | ERICKSON SHAWN DAVID | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286812-A1 | GPR119 Receptor Agonists | GPR119, GPR27, GPR139 | CYP3A4 1503/4885FLT3 2186/4885POLB 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.