SCHEMBL4352652

SCHEMBL4352652

Cc1cc(C(=O)c2ccc(Cl)c(C)c2)ccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
SRD5A2 P31213 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
TAS1R2 Q8TE23 1/20 0.53
VCAM1 P19320 2/20 0.50
LMNA P02545 3/20 0.47
NPC1 O15118 1/20 0.47
MITF O75030 1/20 0.47
POLB P06746 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
ALDH1A1 P00352 4/20 0.46
TSHR P16473 2/20 0.46
MAPT P10636 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9325925 0.90 VCAM1 (0.57) HTTSMN1; SMN2SRD5A2VCAM1LMNA
SCHEMBL22193831 0.87 PARP1 (0.50) HTTSMN1; SMN2SRD5A2TAS1R3TAS1R1
SCHEMBL29554593 0.84 MAPT (0.52) HTTSMN1; SMN2TAS1R3TAS1R1TAS1R2
SCHEMBL312135 0.84 MAPT (0.52) HTTSMN1; SMN2TAS1R3TAS1R1TAS1R2
SCHEMBL2972020 0.84 TAS1R3 (0.51) HTTSMN1; SMN2SRD5A2TAS1R3TAS1R1
SCHEMBL703101 0.84 TSHR (0.65) SMN1; SMN2SRD5A2TAS1R3TAS1R1TAS1R2
SCHEMBL14894712 0.83 TAS1R3 (0.50) HTTSMN1; SMN2TAS1R3TAS1R1TAS1R2
SCHEMBL2467682 0.83 TAS1R3 (0.50) SMN1; SMN2TAS1R3TAS1R1TAS1R2LMNA
SCHEMBL11025910 0.83 TAS1R3 (0.50) HTTSMN1; SMN2SRD5A2TAS1R3TAS1R1
Hydrogen Sulfide SCHEMBL28759691 0.83 TSHR (0.63) SMN1; SMN2SRD5A2TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032019-A1 POSITIVE OSMOSIS MEMBRANE AND APPLICATION FOR SAME 三井化学株式会社 2020-02-13 WO disclosed
WO-2019189547-A1 FORWARD OSMOSIS MEMBRANE AND USE THEREOF 三井化学株式会社 2019-10-03 WO disclosed
WO-2019189548-A1 METHOD FOR PRODUCING SOLUTION HAVING REDUCED SOLUTE CONCENTRATION 三井化学株式会社 2019-10-03 WO disclosed
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
EP-1788649-B1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
US-20100167165-A1 COPOLYMER, POLYMER ELECTROLYTE, AND USE THEREOF SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-01 US disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
US-20070231671-A1 Catalyst Material For Use In Fuel Cell, Catalyst Membrane, Membrane Electrode Assembly and Fuel Cell FUJIFILM CORPORATION 2007-10-04 US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 US disclosed
US-7245851-B2 Electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2007-07-17 US disclosed
EP-1788649-A1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE Mitsui Chemicals, Inc. (JP) 2007-05-23 EP disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed