Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352652 | 0.90 | HTT (0.53) | VCAM1TDP1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL22193831 | 0.86 | PARP1 (0.50) | VCAM1SRD5A2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13176761 | 0.85 | ATM (0.55) | VCAM1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL333237 | 0.82 | SRD5A2 (0.78) | VCAM1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL10007010 | 0.82 | SMN1; SMN2 (0.71) | ATMTDP1L3MBTL1SRD5A2ALDH1A1 | |
| SCHEMBL166495 | 0.82 | SMN1; SMN2 (0.71) | ATMTDP1L3MBTL1SRD5A2ALDH1A1 | |
| SCHEMBL27893118 | 0.81 | ALDH1A1 (0.56) | ATMTDP1L3MBTL1SRD5A2ALDH1A1 | |
| SCHEMBL12337417 | 0.81 | ALDH1A1 (0.61) | ATMTDP1L3MBTL1SRD5A2ALDH1A1 | |
| SCHEMBL703101 | 0.80 | TSHR (0.65) | TDP1L3MBTL1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13236538 | 0.79 | TDP1 (0.69) | ATMTDP1L3MBTL1SRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225991-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF ACUTE INTERMITTENT PORPHYRIA | VESTLANDETS INNOVASJONSSELSKAP AS (NO) | 2023-07-20 | — | — | US | disclosed |
| CN-105418393-B | Two step one-pot synthesis methods of meta position substituted benzophenone class compound | 陕西师范大学 | 2018-07-10 | — | — | CN | disclosed |
| CN-105418393-A | Two-step one-pot synthesis method for meta-substituted diphenyl ketone compound | UNIV SHAANXI NORMAL | 2016-03-23 | — | — | CN | disclosed |
| EP-0268112-B1 | A novel aromatic polyether and a process for producing a polyether | ASAHI CHEMICAL IND (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4931530-A | Novel aromatic polyether and a process for producing an ether | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0268112-A2 | A novel aromatic polyether and a process for producing a polyether | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225991-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF ACUTE INTERMITTENT PORPHYRIA | HMBS, POR, CYP2A13 | VCAM1 4637/4885ATM 3906/4885TDP1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.