SCHEMBL609919

SCHEMBL609919

NC(=S)c1ccccc1C(N)=S

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
HSD17B10 Q99714 3/20 0.42
MAPT P10636 3/20 0.42
TSHR P16473 2/20 0.42
TP53 P04637 1/20 0.42
TYR P14679 1/20 0.42
TAS2R38 P59533 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
PKM P14618 1/20 0.41
GAA P10253 2/20 0.39
METAP2 P50579 1/20 0.39
ALOX15 P16050 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3066108 0.87 F2 (0.44) ALDH1A1HSD17B10MAPTTSHRTP53
SCHEMBL609918 0.87 KDM4E (0.56) ALDH1A1HSD17B10MAPTTSHRKDM4E
SCHEMBL13964794 0.85 BCAT2 (0.43) ALDH1A1HSD17B10MAPTTSHRTP53
SCHEMBL1975371 0.84 ALDH1A1 (0.67) ALDH1A1HSD17B10MAPTKDM4EHPGD
SCHEMBL31253333 0.83 MAPT (0.46) ALDH1A1HSD17B10MAPTTSHRTP53
SCHEMBL2552123 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10MAPTTSHRKDM4E
SCHEMBL11568888 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10MAPTTSHRKDM4E
SCHEMBL31451521 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10MAPTTSHRKDM4E
SCHEMBL165079 0.83 MAPT (0.46) ALDH1A1HSD17B10MAPTTSHRTP53
SCHEMBL28787233 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPTTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090133810-A1 Production method and filter comprising non woven fabric and/or filtering injector structures or sheets which are obtained using said method and which are intended for the filtration and elimination of legionella pneumophila in any installation at risk from legionella pneumophila proliferation PENALVA JOAQUIN ESPUELAS 2009-05-28 US claimed
US-20070202770-A1 Production Method and Filter Comprising Non Woven Fabric and/or Filtering Injector Structures or Sheets Which are Obtained Using Said Method and Which are Intended for the Filtration and Which are Intended for the Filtration and Elimination of Legionella Pneumofila in any Installation at Risk From Legionella Pneumofila Proliferation PENALVA JOAQUIN E 2007-08-30 US claimed
EP-1738812-A1 PRODUCTION METHOD, AND FILTER COMPRISING NON-WOVEN FABRIC AND/OR FILTERING INJECTOR STRUCTURES OR SHEETS WHICH ARE OBTAINED USING SAID METHOD AND WHICH ARE INTENDED FOR THE FILTRATION AND ELIMINATION OF LEGIONELLA PNEUMOPHILA IN ANY INSTALLATION WITH A RISK OF LEGIONELLA PNEUMOPHILA PROLIFERATION Espuelas Peñalva, Joaquin (ES) 2007-01-03 EP claimed
CN-118146128-A Thioamide compound, preparation method thereof and application thereof in fruit and vegetable preservation 湘潭大学 2024-06-07 CN disclosed
CN-116323610-A Pyrazolo [3,4-b ] pyridine-4-carboxamide nitrification inhibitors 欧洲化学安特卫普公司 2023-06-23 CN disclosed
CN-116234786-A N-heterocyclic compounds as nitrification inhibitors 欧洲化学安特卫普公司 2023-06-06 CN disclosed
EP-2857446-B1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-03-07 EP disclosed
US-9790359-B2 Tread rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-10-17 US disclosed
US-20150099823-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2015-04-09 US disclosed
EP-2857446-A1 TREAD RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2015-04-08 EP disclosed
US-8334339-B2 Conjugated diene-based polymer, conjugated diene-based polymer composition, and process for producing conjugated diene-based polymer SUMITOMO CHEMICAL CO., LTD. (JP) 2012-12-18 US disclosed
US-20070202770-A1 Production Method and Filter Comprising Non Woven Fabric and/or Filtering Injector Structures or Sheets Which are Obtained Using Said Method and Which are Intended for the Filtration and Which are Intended for the Filtration and Elimination of Legionella Pneumofila in any Installation at Risk From Legionella Pneumofila Proliferation PENALVA JOAQUIN E 2007-08-30 US disclosed
EP-1738812-A1 PRODUCTION METHOD, AND FILTER COMPRISING NON-WOVEN FABRIC AND/OR FILTERING INJECTOR STRUCTURES OR SHEETS WHICH ARE OBTAINED USING SAID METHOD AND WHICH ARE INTENDED FOR THE FILTRATION AND ELIMINATION OF LEGIONELLA PNEUMOPHILA IN ANY INSTALLATION WITH A RISK OF LEGIONELLA PNEUMOPHILA PROLIFERATION Espuelas Peñalva, Joaquin (ES) 2007-01-03 EP disclosed
EP-0783326-B1 PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF DOW CHEMICAL CO (US) 2004-02-04 EP disclosed
EP-0783326-A1 PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF THE DOW CHEMICAL COMPANY (US) 1997-07-16 EP disclosed
WO-1996007435-A1 PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF THE DOW CHEMICAL COMPANY (US) 1996-03-14 WO disclosed
EP-0662842-A1 PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF THE DOW CHEMICAL COMPANY (US) 1995-07-19 EP disclosed
WO-1993020852-A2 MACROCYCLIC CHELATING AGENTS, CHELATES AND CONJUGATES THEREOF THE DOW CHEMICAL COMPANY (US) 1993-10-28 WO disclosed
US-5143967-A Sulfur cured natural rubber dispersed with carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-09-01 US disclosed
EP-0074783-A1 Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5R) penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor PFIZER INC. (US) 1983-03-23 EP disclosed