⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866810 | 0.78 | HDAC3 (0.41) | — | |
| SCHEMBL2902587 | 0.77 | — | — | |
| SCHEMBL788322 | 0.77 | — | — | |
| SCHEMBL3305420 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL28237658 | 0.75 | — | — | |
| SCHEMBL24622316 | 0.75 | — | — | |
| SCHEMBL7771068 | 0.75 | — | — | |
| SCHEMBL7771072 | 0.75 | — | — | |
| SCHEMBL6980552 | 0.73 | — | — | |
| SCHEMBL8995940 | 0.73 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432653-B1 | SEPARATION OF CELLS FROM LYMPHS OR MYELOID LINAGE WITH BONDING AND CONTACTING CELLS | AVENTIS PHARMACEUTICALS INC. | 2002-08-13 | — | — | US | claimed |
| US-6143508-A | CONTACTING MIXTURE OF CELLS WITH SOLID SUPPORT HAVING HIGH DENSITY OF SPECIFIC RECEPTOR SITES, WHEREBY CELLS HAVING COMPLEMENTARY LIGAND BECOME BOUND TO SURFACE AND MAY BE RELEASED FROM RECEPTORS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 2000-11-07 | — | — | US | claimed |
| JP-9075090-A | — | — | None | — | — | JP | disclosed |
| WO-2021154997-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2009031818-A2 | BIOMARKER FOR PURIFICATION OR IDENTIFICATION OF MESENCHYMAL STEM CELLS AND METHODS OF PURIFICATION OF MESENCHYMAL STEM CELLS BY USING IT | GENEXEL-SEIN. INC. (KR) | 2009-03-12 | — | — | WO | disclosed |
| EP-0888779-B1 | STERILE PROTECTIVE AGENT AND METHOD FOR STERILIZATION | ASAHI MEDICAL CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6572820-B2 | Sterilization-protecting agent and sterilization method | ASAHI MEDICAL CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-6432653-B1 | SEPARATION OF CELLS FROM LYMPHS OR MYELOID LINAGE WITH BONDING AND CONTACTING CELLS | AVENTIS PHARMACEUTICALS INC. | 2002-08-13 | — | — | US | disclosed |
| EP-0701130-B1 | Device and process for cell capture and recovery | RORER PHARM PROD INC (US) | 2002-05-22 | — | — | EP | disclosed |
| US-20020044884-A1 | STERILIZATION- PROTECTING AGENT AND STERILIZATION METHOD | ASAHI KASEI KURARAY MEDICAL CO., LTD. (JP) | 2002-04-18 | — | — | US | disclosed |
| CN-1307640-A | Cell separation device and separation method | ASAHI CHEMICAL IND (JP) | 2001-08-08 | — | — | CN | disclosed |
| EP-0114286-A2 | Semi-permeable encapsulated membranes, process for their production and their use | ALIGENA AG (CH) | 1984-08-01 | — | — | EP | disclosed |
| EP-0111714-A2 | Dynamic membranes for reverse osmosis and ultrafiltration with good flow qualities | ALIGENA AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0082355-A2 | Semipermeable membranes of modified polystyrene, process for their manufacture and their use | ALIGENA AG (CH) | 1983-06-29 | — | — | EP | disclosed |
| EP-0061424-A2 | Semipermeable membranes comprising modified polysulfones, process for their preparation and their use | ALIGENA AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| EP-0047953-A2 | Semipermeable composite membranes comprising modified polyvinyl alcohol, process for their preparation and their use | ALIGENA AG (CH) | 1982-03-24 | — | — | EP | disclosed |
| EP-0026399-A1 | Porous semipermeable cellulose acetate membranes modified by ionic groups, process for their production and their use | ALIGENA AG (CH) | 1981-04-08 | — | — | EP | disclosed |
| EP-0025973-A2 | Porous semipermeable membrane based on polyacrylonitrile modified by amidoxime groups, process for its preparation and their use | ALIGENA AG (CH) | 1981-04-01 | — | — | EP | disclosed |
| US-4238328-A | ADSORBENT COMPRISING POLYNITROGEN COMPOUND, A CARBOXYLIC ACID AND A CROSSLINKING COMPOUND | CIBA-GEIGY CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4144190-A | FOR HEAVY METAL IONS | CIBA-GEIGY AG (CH) | 1979-03-13 | — | — | US | disclosed |