SCHEMBL4353153

SCHEMBL4353153

CC(C)(c1ccc(O)cc1)c1ccc(O)c(C2CO2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.50
ESR2 Q92731 4/20 0.50
HPGD P15428 4/20 0.50
TSHR P16473 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP3A4 P08684 2/20 0.50
AR P10275 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ALDH1A1 P00352 4/20 0.44
KLF10 Q13118 1/20 0.40
ALOX15 P16050 3/20 0.38
ALOX12 P18054 1/20 0.38
RORC P51449 1/20 0.37
LMNA P02545 2/20 0.37
TYR P14679 2/20 0.37
TP53 P04637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15238949 0.89 ESR1 (0.47) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL6927713 0.83 ALDH1A1 (0.52) ESR1HPGDTSHRHSD17B10ALDH1A1
SCHEMBL20717757 0.78 ESR1 (0.50) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL2694148 0.78 ESR1 (0.46) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL7929735 0.77 DYRK1A (0.40) HSD17B10CYP3A4ARALDH1A1ALOX15
SCHEMBL2340495 0.77 ESR1 (0.49) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL29458615 0.77 ESR1 (0.49) ESR1ESR2HPGDTSHRHSD17B10
Bisphenol A SCHEMBL156686 0.76 ESR1 (0.67) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL4347657 0.75 KLF10 (0.51) ESR1ESR2HPGDTSHRHSD17B10
SCHEMBL30549330 0.74 ESR1 (0.70) ESR1ESR2HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1542084-B1 BINDER RESIN FOR TONER AND TONERS MITSUI CHEMICALS INC (JP) 2013-10-02 EP disclosed
US-8247153-B2 Process for producing resin microparticles for a toner raw material MITSUI CHEMICALS, INC. (JP) 2012-08-21 US disclosed
US-20090020900-A1 Process for Producing Resin Microparticles for a Toner Raw Material MITSUI CHEMICALS, INC. (JP) 2009-01-22 US disclosed
US-20070082285-A1 Resin microparticle as raw material for toner, aqueous dispersed system thereof and toner MITSUI CHEMICALS, INC. (JP) 2007-04-12 US disclosed
US-7115702-B2 Binder resin for toner and toners MITSUI CHEMICALS, INC. (JP) 2006-10-03 US disclosed
US-20060167214-A1 Good in low-temperature fixing property, offset resistance and smear resistance; environmentaly safe (no bisphenol A structure and tin) MITSUI CHEMICALS, INC. (JP) 2006-07-27 US disclosed
EP-1679552-A1 RESIN MICROPARTICLE AS RAW MATERIAL FOR TONER, DISPERSION SYSTEM THEREOF AND TONER Mitsui Chemicals, Inc. (JP) 2006-07-12 EP disclosed
EP-1542084-A1 BINDER RESIN FOR TONER AND TONERS Mitsui Chemicals, Inc. (JP) 2005-06-15 EP disclosed