Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353153 | 0.83 | ESR1 (0.50) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL15238949 | 0.82 | ESR1 (0.47) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| SCHEMBL11308536 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL7929735 | 0.75 | DYRK1A (0.40) | ALDH1A1ALOX15HSD17B10LMNATYR | |
| SCHEMBL3133679 | 0.74 | CYP2D6 (0.54) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Methane SCHEMBL27697714 | 0.72 | CYP2D6 (0.52) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL3846964 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL14973391 | 0.71 | CYP2D6 (0.53) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL50705 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL29358687 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646093-B2 | Extruding auxiliary for cement materials, a mortar thickening agent, an underwater concrete thickening agent, a ceramics forming binder and a moisturizer for hair cosmetics; water and shape retention. | MITSUI CHEMICALS, INC. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6515050-B1 | An extruding auxiliary using the above novel water-soluble polyurethane; additive for underwater concrete | MITSUI CHEMICALS, INC. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | MITSUI TAKEDA CHEMICALS, INC. (JP) | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | BMI1, ASH2L, HAT1 | ALDH1A1 804/4885HPGD 1225/4885ALOX15 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.