Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.48 |
| ▸ | CA2 | P00918 | 12/20 | 0.48 |
| ▸ | CA12 | O43570 | 11/20 | 0.48 |
| ▸ | CA9 | Q16790 | 11/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 6/20 | 0.45 |
| ▸ | CA4 | P22748 | 6/20 | 0.45 |
| ▸ | CA6 | P23280 | 6/20 | 0.45 |
| ▸ | CA5A | P35218 | 6/20 | 0.45 |
| ▸ | CA7 | P43166 | 6/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xipamide SCHEMBL29377965 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9RORC | |
| Xipamide SCHEMBL6711167 | 1.00 | CA1 (0.48) | CA1CA2CA12CA9RORC | |
| Xipamide SCHEMBL6898106 | 0.95 | CA12 (0.48) | CA1CA2CA12CA9RORC | |
| Xipamide SCHEMBL8196525 | 0.94 | CA1 (0.46) | CA1CA2CA12CA9RORC | |
| Xipamide SCHEMBL28193437 | 0.83 | CA1 (0.60) | CA1CA2CA12CA9RORC | |
| Tripamide SCHEMBL4442559 | 0.79 | KDM4E (0.46) | CA1CA2CA12CA9POLB | |
| SCHEMBL10717512 | 0.78 | CISD1 (0.56) | CA1CA2CA12CA9CA3 | |
| Indapamide SCHEMBL28086620 | 0.78 | CA1 (0.74) | CA1CA2CA12CA9POLB | |
| SCHEMBL31338871 | 0.75 | LMNA (0.53) | CA1CA2CA12CA9RORC | |
| SCHEMBL11246918 | 0.75 | LMNA (0.53) | CA1CA2CA12CA9RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6602 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090360-A1 | FUSED PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | claimed |
| US-20260108529-A1 | FUSED AMINO PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, ACUTE SENSORINEURAL HEARING LOSS, AGE-RELATED HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4482481-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES | SOM INNOVATION BIOTECH S A (ES) | 2025-11-12 | — | — | EP | claimed |
| US-20250206779-A1 | ANGIOTENSIN-(1-9) ANALOGUE BASED ON D AMINO ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | UNIVERSIDAD DE CHILE (CL) | 2025-06-26 | — | — | US | claimed |
| US-20250152567-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2025-05-15 | — | — | US | claimed |
| WO-2025050228-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A PEPTIDE OR A COMBINATION OF PEPTIDES AGONISTIC TO THE MAS, AT1 AND AT2 RECEPTORS | PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) | 2025-03-13 | — | — | WO | claimed |
| US-20250057876-A1 | METHODS FOR TREATING AND/OR PREVENTING LYMPHANGIOGENESIS-ASSOCIATED DISEASES BY USING GOLD NANOCLUSTERS | GOLDRED NANOBIOTECH CO., LTD. (TW) | 2025-02-20 | — | — | US | claimed |
| EP-4482481-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF DYSTROPHINOPATHIES | Som Innovation Biotech, S.L. (ES) | 2025-01-01 | — | — | EP | claimed |
| US-12102653-B2 | Ligand regulated protein-protein interaction system | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2024-10-01 | — | — | US | claimed |
| US-4855289-A | Combination of two active substances | WESTER PER O (SE) | 1989-08-08 | — | — | US | claimed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0078469-B1 | PHARMACEUTICAL COMPOSITION | Beiersdorf Aktiengesellschaft (DE) | 1986-04-09 | — | — | EP | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0032725-B1 | NOVEL ALDEHYDE ADDUCTS OF TRIAMTERENE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1985-05-08 | — | — | EP | claimed |
| US-4490368-A | EQUILIBRIUM OF BLOOD METAL CONCENTRATION | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-12-25 | — | — | US | claimed |
| EP-0120165-A2 | A preparation and a process for achieving regional weight control | Greenway III, Frank L. (US) | 1984-10-03 | — | — | EP | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-4285947-A | DIURETICS, HYPOTENSIVES | INTERX RESEARCH CORPORATION (US) | 1981-08-25 | — | — | US | claimed |
| EP-0032725-A1 | Novel aldehyde adducts of triamterene and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-07-29 | — | — | EP | claimed |