Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4362282 | 0.85 | THRB (0.60) | THRATHRB | |
| SCHEMBL5618887 | 0.82 | THRA (0.63) | THRATHRB | |
| SCHEMBL5618890 | 0.82 | THRA (0.63) | THRATHRB | |
| SCHEMBL6099194 | 0.80 | THRA (0.61) | THRATHRB | |
| SCHEMBL5618676 | 0.80 | THRA (0.61) | THRATHRB | |
| SCHEMBL4539467 | 0.78 | THRA (0.69) | THRATHRB | |
| SCHEMBL4355360 | 0.78 | THRA (0.65) | THRATHRB | |
| SCHEMBL4358608 | 0.77 | THRA (0.76) | THRATHRB | |
| SCHEMBL4358602 | 0.77 | THRA (0.76) | THRATHRB | |
| SCHEMBL4536234 | 0.77 | THRA (0.76) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |