Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353250 | 0.85 | THRA (0.60) | THRBTHRA | |
| SCHEMBL7955180 | 0.79 | THRA (0.63) | THRBTHRA | |
| SCHEMBL4566244 | 0.79 | THRA (0.63) | THRBTHRA | |
| SCHEMBL5618359 | 0.79 | THRA (0.63) | THRBTHRA | |
| SCHEMBL4539467 | 0.78 | THRA (0.69) | THRBTHRA | |
| SCHEMBL3707431 | 0.77 | THRA (0.59) | THRBTHRA | |
| SCHEMBL5618153 | 0.77 | THRA (0.64) | THRBTHRA | |
| SCHEMBL5619285 | 0.76 | THRA (1.00) | THRBTHRA | |
| SCHEMBL4355360 | 0.76 | THRA (0.65) | THRBTHRA | |
| SCHEMBL5549351 | 0.76 | THRB (0.79) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | claimed |
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |