Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537918 | 0.86 | PTPN2 (0.43) | PTPN2PTPN1POLBNPSR1SMN1; SMN2 | |
| SCHEMBL4356473 | 0.86 | PTPN2 (0.43) | PTPN2PTPN1POLBNPSR1SMN1; SMN2 | |
| SCHEMBL4349922 | 0.86 | PTPN2 (0.43) | PTPN2PTPN1POLBNPSR1SMN1; SMN2 | |
| SCHEMBL4347925 | 0.85 | USP30 (0.40) | BRD4 | |
| SCHEMBL4355152 | 0.84 | CHRM2 (0.38) | PKMMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4534568 | 0.84 | CA12 (0.39) | BRD4CA12CA1CA2CA7 | |
| SCHEMBL4353588 | 0.84 | PIK3CA (0.43) | LMNA | |
| SCHEMBL4356151 | 0.83 | GAA (0.42) | POLBSMN1; SMN2GAA | |
| SCHEMBL4347963 | 0.83 | NPC1 (0.46) | TSHRALDH1A1LMNACA12CA1 | |
| SCHEMBL4347874 | 0.83 | KDM1A (0.41) | BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |