Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355488 | 0.90 | ALDH1A1 (0.35) | ALDH1A1USP30PIK3CACA1CA2 | |
| SCHEMBL4537918 | 0.88 | PTPN2 (0.43) | ALDH1A1PIK3CACA1CA2CA9 | |
| SCHEMBL4356473 | 0.88 | PTPN2 (0.43) | ALDH1A1PIK3CACA1CA2CA9 | |
| SCHEMBL4349922 | 0.88 | PTPN2 (0.43) | ALDH1A1PIK3CACA1CA2CA9 | |
| SCHEMBL4355702 | 0.86 | PIK3CA (0.37) | CHRM2USP30PIK3CA | |
| SCHEMBL4347925 | 0.85 | USP30 (0.40) | USP30PIK3CA | |
| SCHEMBL4347963 | 0.84 | NPC1 (0.46) | MGLLALDH1A1PIK3CACA1CA2 | |
| SCHEMBL4356151 | 0.84 | GAA (0.42) | PIK3CASMN1; SMN2 | |
| SCHEMBL4353464 | 0.84 | CYP3A4 (0.37) | ALDH1A1USP30SMN1; SMN2 | |
| SCHEMBL4353473 | 0.84 | PTPN2 (0.47) | ALDH1A1CA1CA2CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |