Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535480 | 0.89 | LMNA (0.42) | GAASMN1; SMN2GPR119PIK3CACYP2D6 | |
| SCHEMBL4356473 | 0.87 | PTPN2 (0.43) | SMN1; SMN2PIK3CASLC9A1CYP2C19POLB | |
| SCHEMBL4537918 | 0.87 | PTPN2 (0.43) | SMN1; SMN2PIK3CASLC9A1CYP2C19POLB | |
| SCHEMBL4349922 | 0.87 | PTPN2 (0.43) | SMN1; SMN2PIK3CASLC9A1CYP2C19POLB | |
| SCHEMBL4355702 | 0.87 | PIK3CA (0.37) | GPR119PIK3CA | |
| SCHEMBL4353588 | 0.86 | PIK3CA (0.43) | L3MBTL1GPR119EPHX2PIK3CACYP2C9 | |
| SCHEMBL4355152 | 0.84 | CHRM2 (0.38) | SMN1; SMN2PIK3CA | |
| SCHEMBL4347925 | 0.84 | USP30 (0.40) | GPR119EPHX2PIK3CA | |
| SCHEMBL4531447 | 0.83 | PIK3CA (0.44) | GPR119PIK3CASLC9A1 | |
| SCHEMBL4353423 | 0.83 | PIK3CA (0.38) | GPR119PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |