Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23666 | 0.83 | — | — | |
| SCHEMBL107822 | 0.83 | — | — | |
| SCHEMBL120653 | 0.83 | — | — | |
| Bicarbonate SCHEMBL11385890 | 0.80 | ALDH1A1 (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ammonia Solution, Strong SCHEMBL27766240 | 0.79 | — | — | |
| Water SCHEMBL28326998 | 0.79 | — | — | |
| Phosphoric Acid SCHEMBL5963777 | 0.79 | LAP3 (0.32) | CA2 | |
| SCHEMBL9721022 | 0.79 | — | — | |
| Bicarbonate SCHEMBL11401864 | 0.77 | GABRP (0.33) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Isobutane SCHEMBL3698012 | 0.76 | TP53 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574771-B2 | Rechargeable lithium battery | SAMSUNG SDI CO., LTD. (KR) | 2013-11-05 | — | — | US | disclosed |
| US-7494746-B2 | Electrolyte for rechargeable lithium battery, and rechargeable lithium battery including same | SAMSUNG SDI CO., LTD. (KR) | 2009-02-24 | — | — | US | disclosed |
| US-20080118843-A1 | Electrolyte for rechargeable lithium battery, and rechargeable lithium battery including same | SAMSUNG SDI CO., LTD., A CORPORATION ORGANIZED UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) | 2008-05-22 | — | — | US | disclosed |
| US-20070154810-A1 | Rechargeable lithium battery | SAMSUNG SDI CO., LTD. (KR) | 2007-07-05 | — | — | US | disclosed |