Beta-Naphthoflavone

Beta-Naphthoflavone

SCHEMBL43538

O=c1cc(-c2ccccc2)oc2ccc3ccccc3c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 1.00
AHR P35869 5/20 1.00
CYP1A1 P04798 3/20 1.00
CYP1A2 P05177 3/20 1.00
PAX8 Q06710 2/20 1.00
FYN P06241 1/20 1.00
MAPK3 P27361 1/20 1.00
NPC1 O15118 3/20 0.78
TDP1 Q9NUW8 2/20 0.78
RAB9A P51151 2/20 0.78
TP53 P04637 3/20 0.65
CYP3A4 P08684 3/20 0.65
CYP2D6 P10635 2/20 0.65
MAPT P10636 2/20 0.65
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
ABCB1 P08183 2/20 0.63
CYP19A1 P11511 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-Naphthoflavone SCHEMBL29357406 1.00 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
Beta-Naphthoflavone SCHEMBL29881204 1.00 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
Alpha-Naphthoflavone SCHEMBL3665037 0.90 CYP1A1 (0.82) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL15397111 0.88 AHR (0.78) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL13066020 0.88 TDP1 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL25109125 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL15397001 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL22525848 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL29361866 0.84 TDP1 (0.74) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL7116289 0.84 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2194 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119587702-A Pharmaceutical composition capable of improving bioavailability of oral statin drugs and application thereof 强生化学制药厂股份有限公司 2025-03-11 CN claimed
CN-117897141-A Flavonoid-rich spray-dried powder 梅西大学 2024-04-16 CN claimed
EP-4284386-A1 FLAVONOID-ENRICHED SPRAY-DRIED POWDER Massey University (NZ) 2023-12-06 EP claimed
CN-117153453-A Conductive polymer composite material, preparation method thereof and grounding electrode comprising conductive polymer composite material 广东和通科技有限公司 2023-12-01 CN claimed
CN-113797214-B Composition containing cyclo-olivil 4' -glycoside and preparation method and application thereof 江西普正制药股份有限公司 2023-11-24 CN claimed
CN-116144163-B Temperature-resistant conductive polymer composite material and preparation method and application thereof 广东腐蚀科学与技术创新研究院 2023-06-30 CN claimed
CN-116144163-A Temperature-resistant conductive polymer composite material and preparation method and application thereof 广东腐蚀科学与技术创新研究院 2023-05-23 CN claimed
CN-115536958-B Corrosion-resistant conductive polymer composite material and preparation method and application thereof 广东腐蚀科学与技术创新研究院 2023-04-07 CN claimed
US-11596657-B2 Use of AhR agonist for the preventive or curative treatment of metabolic syndrome and the associated disorders INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2023-03-07 US claimed
CN-115536958-A Corrosion-resistant conductive polymer composite material and preparation method and application thereof 广东腐蚀科学与技术创新研究院 2022-12-30 CN claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed
WO-2000062769-A2 USE OF AP-1 ACTIVATORS TO TREAT GLAUCOMA AND OCULAR HYPERTENSION ALCON LABORATORIES, INC. (US) 2000-10-26 WO claimed
US-6117610-A A MIXTURE OR A REACTION PRODUCT OF A PHENOLIC RESIN AND AN O-DIAZONAPHTHOQUINONE, A NON-BASIC INFRARED ABSORBER AND A DISSOLUTION INHIBITOR INSENSITIVE TO ACTINIC RADIATION; POSITIVE AND NEGATIVE LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC (US) 2000-09-12 US claimed
US-6066642-A FOR SELECTIVELY BLOCKING THE A3 ADENOSINE RECEPTOR OF A MAMMAL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2000-05-23 US claimed
EP-0954304-A2 METHODS FOR REGULATING NICOTINE METABOLISM Nicogen Inc. (CA) 1999-11-10 EP claimed
US-5854010-A Bioassay for detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like compounds and novel recombinant cell line useful therefor XENOBIOTIC DETECTION SYSTEMS INTERNATIONAL, INC. 1998-12-29 US claimed
WO-1998003171-A2 USE OF INHIBITORS OF CYP2A6 FOR REGULATING NICOTINE METABOLISM NICOGEN INC. (CA) 1998-01-29 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
US-5589504-A Treatment of newborn jaundice CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-31 US claimed
WO-1994023715-A1 USE OF FLAVONOIDS TO TREAT MULTIDRUG RESISTANT CANCER CELLS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1994-10-27 WO claimed