Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 11/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.82 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.82 |
| ▸ | PRKDC | P78527 | 3/20 | 0.82 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | PDE5A | O76074 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.82 |
| ▸ | TACR2 | P21452 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Naphthoflavone SCHEMBL29881204 | 0.90 | ABCG2 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Beta-Naphthoflavone SCHEMBL29357406 | 0.90 | ABCG2 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Alpha-Naphthoflavone SCHEMBL29351090 | 0.90 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Alpha-Naphthoflavone SCHEMBL121594 | 0.90 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Beta-Naphthoflavone SCHEMBL43538 | 0.90 | ABCG2 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Alpha-Naphthoflavone SCHEMBL1906540 | 0.83 | CYP1A1 (0.80) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| Alpha-Naphthoflavone SCHEMBL17292887 | 0.83 | CYP1A1 (0.84) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL13066020 | 0.80 | TDP1 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PAX8 | |
| SCHEMBL30917246 | 0.80 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1ABCG2PRKDC | |
| SCHEMBL15397111 | 0.80 | AHR (0.78) | CYP1A1CYP1A2ABCG2PAX8TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237775-A1 | COMPOSITION FOR TOPICAL USE | Saurat, Jean Hilaire (CH) | 2010-10-13 | — | — | EP | claimed |
| WO-2009093207-A1 | COMPOSITION FOR TOPICAL USE | SAURAT JEAN HILAIRE (CH) | 2009-07-30 | — | — | WO | claimed |