Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.72 |
| ▸ | AHR | P35869 | 2/20 | 0.72 |
| ▸ | FYN | P06241 | 1/20 | 0.72 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397111 | 0.85 | AHR (0.78) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Beta-Naphthoflavone SCHEMBL43538 | 0.84 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Beta-Naphthoflavone SCHEMBL29881204 | 0.84 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| Beta-Naphthoflavone SCHEMBL29357406 | 0.84 | ABCG2 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| SCHEMBL1740996 | 0.83 | ABCG2 (0.71) | ABCG2CYP1A1CYP1A2NPC1RAB9A | |
| SCHEMBL13066020 | 0.82 | TDP1 (1.00) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| 4'-Methoxyflavone SCHEMBL29573796 | 0.82 | MAOB (1.00) | ABCG2NPC1RAB9AKDM4EALDH1A1 | |
| 4'-Methoxyflavone SCHEMBL311931 | 0.82 | MAOB (1.00) | ABCG2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL25109125 | 0.82 | AHR (0.72) | ABCG2CYP1A1CYP1A2PAX8AHR | |
| SCHEMBL22525848 | 0.82 | AHR (0.72) | ABCG2CYP1A1CYP1A2PAX8AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |