Beta-Naphthoflavone

Beta-Naphthoflavone

SCHEMBL29357406

O=c1cc(-c2ccccc2)oc2ccc3ccccc3c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 5/20 1.00
AHR P35869 5/20 1.00
CYP1A1 P04798 3/20 1.00
CYP1A2 P05177 3/20 1.00
PAX8 Q06710 2/20 1.00
FYN P06241 1/20 1.00
MAPK3 P27361 1/20 1.00
NPC1 O15118 3/20 0.78
TDP1 Q9NUW8 2/20 0.78
RAB9A P51151 2/20 0.78
TP53 P04637 3/20 0.65
CYP3A4 P08684 3/20 0.65
CYP2D6 P10635 2/20 0.65
MAPT P10636 2/20 0.65
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
ABCB1 P08183 2/20 0.63
CYP19A1 P11511 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-Naphthoflavone SCHEMBL43538 1.00 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
Beta-Naphthoflavone SCHEMBL29881204 1.00 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
Alpha-Naphthoflavone SCHEMBL3665037 0.90 CYP1A1 (0.82) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL15397111 0.88 AHR (0.78) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL13066020 0.88 TDP1 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL25109125 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL15397001 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL22525848 0.84 AHR (0.72) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL29361866 0.84 TDP1 (0.74) ABCG2AHRCYP1A1CYP1A2PAX8
SCHEMBL7116289 0.84 ABCG2 (1.00) ABCG2AHRCYP1A1CYP1A2PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11596657-B2 Use of AhR agonist for the preventive or curative treatment of metabolic syndrome and the associated disorders INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2023-03-07 US claimed
US-20220273610-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-09-01 US claimed
US-20220143143-A1 USE OF ACTIVATORS OF THE ARYL HYDROCARBON RECEPTOR FOR TREATING GLUTEN-INDUCED GASTROINTESTINAL DISEASES UNIV MCMASTER (CA) 2022-05-12 US claimed
US-20260041667-A1 PRESCRIPTION DIGITAL THERAPEUTICS BECKLEY PSYTECH LTD (GB) 2026-02-12 US disclosed
US-20260035334-A1 METHOD OF SYNTHESIS BECKLEY PSYTECH LTD (GB) 2026-02-05 US disclosed
WO-2025235664-A1 PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2025-11-13 WO disclosed
EP-3522902-B1 PROBIOTIC BACTERIA PRODUCING AN AHR AGONIST AND THEIR USE IN THE TREATMENT OF METABOLIC SYNDROME AND OBESITY INSTITUT NATIONAL DE RECH POUR LAGRICULTURE LALIMENTATION ET LENVIRONNEMENT (FR) 2025-09-03 EP disclosed
EP-4595962-A2 PHARMACEUTICAL COMPOSITION Beckley Psytech Limited (GB) 2025-08-06 EP disclosed
EP-4551940-A2 METHODS AND ASSAYS FOR SECRETOME ACTIVITY ANALYSIS Combangio, Inc. (US) 2025-05-14 EP disclosed
EP-4483957-A2 PHARMACEUTICAL COMPOSITION Beckley Psytech Limited (GB) 2025-01-01 EP disclosed
EP-4463158-A2 NOVEL PRODRUGS DERIVED FROM NICOTINIC ACID AND RIBOSE Mitopower, Inc. (US) 2024-11-20 EP disclosed
US-11518743-B2 Pharmaceutical composition comprising 5-methoxy-N,N-dimethyltryptamine Beckley Psytech Limited (GB) 2022-12-06 US disclosed
US-11518742-B2 Composition comprising a benzoate salt of 5-methoxy-N,N-dimethyltryptamine Beckley Psytech Limited (GB) 2022-12-06 US disclosed
US-20220273610-A1 ANTIMYCOTIC Karl-Franzens-Universität Graz (AT) 2022-09-01 US disclosed
US-20220267267-A1 PHARMACEUTICAL COMPOSITION COMPRISING 5-METHOXY-N,N-DIMETHYLTRYPTAMINE Beckley Psytech Limited (GB) 2022-08-25 US disclosed
US-20220259147-A1 COMPOSITION COMPRISING A BENZOATE SALT OF 5-METHOXY-N,N-DIMETHYLTRYPTAMINE Beckley Psytech Limited (GB) 2022-08-18 US disclosed
EP-4034536-A1 2-ISOINDOL-1,3,4-OXADIAZOLE DERIVATIVES USEFUL AS HDAC6 INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2022-08-03 EP disclosed
US-20220143143-A1 USE OF ACTIVATORS OF THE ARYL HYDROCARBON RECEPTOR FOR TREATING GLUTEN-INDUCED GASTROINTESTINAL DISEASES UNIV MCMASTER (CA) 2022-05-12 US disclosed
WO-2022082106-A1 PEST REPELLENTS AND USES THEREOF Sensorygen, Inc. (US) 2022-04-21 WO disclosed
EP-3941583-A1 COMPOSITION COMPRISING A BENZOATE SALT OF 5-METHOXY-N,N-DIMETHYLTRYPTAMINE Beckley Psytech Limited (GB) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259147-A1 COMPOSITION COMPRISING A BENZOATE SALT OF 5-METHOXY-N,N-DIMETHYLTRYPTAMINE HTR5A, SLC6A4, HTR4 ABCG2 261/4885AHR 1338/4885CYP1A1 798/4885
US-20260035334-A1 METHOD OF SYNTHESIS HTR5A, HTR1A, HTR2C ABCG2 481/4885AHR 1328/4885CYP1A1 541/4885
US-20220273610-A1 ANTIMYCOTIC ETF1, API5, ERG28 ABCG2 388/4885AHR 1952/4885CYP1A1 1358/4885
US-11518742-B2 Composition comprising a benzoate salt of 5-methoxy-N,N-dimethyltryptamine HTR5A, SLC6A4, HTR4 ABCG2 261/4885AHR 1338/4885CYP1A1 798/4885
US-20220267267-A1 PHARMACEUTICAL COMPOSITION COMPRISING 5-METHOXY-N,N-DIMETHYLTRYPTAMINE HTR5A, INMT, HTR1A ABCG2 356/4885AHR 2496/4885CYP1A1 603/4885
US-20260041667-A1 PRESCRIPTION DIGITAL THERAPEUTICS HTR5A, PNMT, NPY5R ABCG2 2345/4885AHR 2328/4885CYP1A1 2750/4885
US-11518743-B2 Pharmaceutical composition comprising 5-methoxy-N,N-dimethyltryptamine HTR5A, INMT, HTR1A ABCG2 356/4885AHR 2496/4885CYP1A1 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.