Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575571 | 0.79 | TP53 (0.50) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL3978958 | 0.78 | TP53 (0.48) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL28227421 | 0.77 | TP53 (0.44) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL1961187 | 0.76 | TP53 (0.47) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL21495096 | 0.76 | TP53 (0.47) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL838659 | 0.76 | TP53 (0.57) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL9447753 | 0.76 | TP53 (0.47) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL28247019 | 0.76 | LMNA (0.43) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL17755076 | 0.73 | LMNA (0.53) | TP53LMNAHTTTDP1IDO1 | |
| SCHEMBL4686827 | 0.73 | TP53 (0.44) | TP53LMNAHTTTDP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |