SCHEMBL4354201

SCHEMBL4354201

CCCCCC=CC[SiH](OC)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.45
TRPV1 Q8NER1 2/20 0.45
LPAR3 Q9UBY5 1/20 0.40
MAPT P10636 3/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
PLA2G4A P47712 1/20 0.40
PAFAH1B2 P68402 1/20 0.40
MGLL Q99685 1/20 0.40
ABHD6 Q9BV23 1/20 0.40
TERT O14746 3/20 0.39
BLM P54132 2/20 0.39
HSD17B10 Q99714 2/20 0.39
FABP4 P15090 2/20 0.39
PTPN1 P18031 2/20 0.39
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
GMNN O75496 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472124 0.98 FAAH (0.48) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL22472145 0.98 FAAH (0.48) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL4365373 0.98 FAAH (0.48) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL4348925 0.98 FAAH (0.48) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL16458603 0.98 FAAH (0.48) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL2283790 0.93 FAAH (0.37) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL6063110 0.84
SCHEMBL22472132 0.79 FAAH (0.47) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL16458874 0.79 FAAH (0.47) FAAHTRPV1LPAR3MAPTKMT2A
SCHEMBL22472123 0.79 FAAH (0.47) FAAHTRPV1LPAR3MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-04-17 US claimed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
US-20220153583-A1 BULK BORON NITRIDE PARTICLES, THERMALLY CONDUCTIVE RESIN COMPOSITION, AND HEAT DISSIPATING MEMBER DENKA COMPANY LIMITED (JP) 2022-05-19 US disclosed
WO-2020196644-A1 BULK BORON NITRIDE PARTICLES, THERMALLY CONDUCTIVE RESIN COMPOSITION, AND HEAT DISSIPATING MEMBER デンカ株式会社 2020-10-01 WO disclosed
US-9127167-B2 Functional reinforcing fillers modified with alkenylalkoxysilane and preparing method of the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-09-08 US disclosed
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-04-17 US disclosed
EP-1989253-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2013-10-02 EP disclosed
EP-2024439-B1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO LTD (JP) 2012-06-27 EP disclosed
US-20090298980-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY CO., LTD. (JP) 2009-12-03 US disclosed
US-20090099321-A1 Curable Silicone Resin Composition and Cured Body Thereof DOW CORNING TORAY COMPANY, LTD. (JP) 2009-04-16 US disclosed
EP-2024439-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2009-02-18 EP disclosed
EP-1989253-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2008-11-12 EP disclosed
WO-2007132932-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-11-22 WO disclosed
WO-2007099863-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-09-07 WO disclosed
WO-2004005404-A1 CURABLE SILICONE RESIN COMPOSITION AND CURED PRODUCT DOW CORNING TORAY SILICONE CO.,LTD. (JP) 2004-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME TST, MSN, TELO2 FAAH 424/4885TRPV1 2927/4885LPAR3 3048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.