Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354447 | 0.90 | THRB (0.54) | TSHRHPGDTHRBHCAR2AKR1B10 | |
| Methacrylic Acid SCHEMBL4142540 | 0.90 | TSHR (0.43) | TSHRHPGDTHRBHCAR2AKR1B10 | |
| Methacrylic Acid SCHEMBL7262507 | 0.88 | THRB (0.56) | TSHRHPGDTHRBHCAR2AKR1B10 | |
| Styrene SCHEMBL7903211 | 0.87 | TSHR (0.52) | TSHRHPGDTHRBHCAR2TDP1 | |
| SCHEMBL7852013 | 0.87 | TSHR (0.55) | TSHRHPGDTHRBHCAR2TDP1 | |
| Methacrylic Acid SCHEMBL7908009 | 0.86 | TSHR (0.69) | TSHRHPGDTHRBHCAR2TDP1 | |
| Styrene SCHEMBL4355403 | 0.86 | TSHR (0.54) | TSHRHPGDTHRBHCAR2TDP1 | |
| Methacrylic Acid SCHEMBL27992784 | 0.85 | THRB (0.54) | TSHRHPGDTHRBHCAR2AKR1B10 | |
| Propene SCHEMBL28187730 | 0.85 | TSHR (0.52) | TSHRHPGDTHRBHCAR2TDP1 | |
| Methacrylic Acid SCHEMBL28298736 | 0.84 | THRB (0.41) | TSHRHPGDTHRBHCAR2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449703-A | Acrylic monomer and free radical catalysts for dentures | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-12 | — | — | US | disclosed |