SCHEMBL4354841

SCHEMBL4354841

N#Cc1cnn(Cc2ccccc2)c1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.51
RECQL P46063 1/20 0.47
TSHR P16473 5/20 0.45
ALDH1A1 P00352 8/20 0.43
LMNA P02545 5/20 0.43
HTT P42858 4/20 0.43
HPGD P15428 4/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPK1 P28482 3/20 0.43
PKM P14618 3/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
KMT2A Q03164 2/20 0.43
CYP19A1 P11511 1/20 0.43
MEN1 O00255 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPBWR1 P48145 2/20 0.42
MAPT P10636 2/20 0.40
PPARG P37231 2/20 0.40
NCOA2 Q15596 2/20 0.40
NCOA1 Q15788 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4361426 0.83 HSD17B10 (0.51) HSD17B10RECQLTSHRALDH1A1LMNA
SCHEMBL4352982 0.82 TSHR (0.51) HSD17B10RECQLTSHRALDH1A1LMNA
SCHEMBL164239 0.82 TSHR (0.59) HSD17B10RECQLTSHRALDH1A1HTT
SCHEMBL4356807 0.77 RECQL (0.55) HSD17B10RECQLTSHRALDH1A1LMNA
SCHEMBL4348519 0.76 HSD17B10 (0.46) HSD17B10RECQLTSHRALDH1A1KDM4E
SCHEMBL26120479 0.72 SMN1; SMN2 (0.47) ALDH1A1HTTKDM4ESMN1; SMN2KMT2A
SCHEMBL4352717 0.70 RECQL (0.51) HSD17B10RECQLTSHRALDH1A1LMNA
SCHEMBL1694603 0.70 ALDH1A1 (0.47) HSD17B10RECQLTSHRALDH1A1LMNA
SCHEMBL31144897 0.70 ALDH1A1 (0.56) TSHRALDH1A1LMNAHPGDKDM4E
SCHEMBL19746474 0.70 PTGS1 (0.49) HSD17B10RECQLTSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
US-20080217617-A1 Thin Film Transistor, Wiring Board and Methods of Manufacturing the Same ZEON CORPORATION (JP) 2008-09-11 US disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed